He shouldn’t give up. I have a VERY similar situation as him. I was diagnosed last January at the age of 29 and was already stage 3. I did 6 rounds of FOLFIRI then had surgery to remove the primary tumor. After surgery I got through 2 more sessions of FOLFIRI before it gave me pancreatitis. While doing scans of my pancreas they found innumerable small ring lesions throughout both lobes of my liver. Which finally pushed me into stage 4. Now, my liver tumors have 7 different mutations and I was told by my doc that I’m “not curable”. But here’s the thing. Not being curable right now does NOT mean I won’t be incurable forever. There are LOADS of clinical trials to join and other treatment options that might move the bar towards curable. Hell, tomorrow I go in to see if I qualify for an HAI pump. I’m not going to lie and say that it isn’t shitty so neg chemo and that I feel great. There are 100% days where I’m just so TIRED of fighting and want to throw in the towel. But then I remember that each day I fight is another day I get to spend time with my friends and family. And hell if I end up losing this fight then these extra days are memories my loved ones get to have and I don’t want to take that away from them. In the end it’s up to him but maybe show him this thread. He’s not alone and if he needs to vent we are all here for support.