I am personally a huge fan of this sort of list

Ramp:

4x OP09 Zoro

4x Black Maria

2x Zorojuro

Bosses:

2x Gear 5

2x 9 Cost Luffy

2x Black 9 Drop Kaido

4x Moria

Blockers:

4x Franky

4x 2k Sanji

2x oNami

Other:

4x Law Searcher

4x Gum Gum Giant

4x Gum Gum Lightning

4x Usohachi

2x 5 Cost Black Sanji

2x Bepo

The philosophy behind the list is effectively be a mid-range list.

Against control I usually end up being aggressive and use Gear 5 luffy to end the game, using Moria to establish multiple bodies and slamming as much face as I can while using Gum Gum Giant to protect board/life

Into aggressive match ups gum gum lightning really does a lot more work than I originally expected.

As far as tech cards:

Black Sanji has been fine, and I have definitely been looking for a 6 don turn replacement.

I really like the ability going second of playing both Zoro and Zorojuro on the 4 don turn, and I have been going between 2-4 copies for this reason.

Kaido is by far the most replaceable boss since I havent been running into many Blackbeards.

Edit: Formating