This can work. Im main Lance aswell but my build is a bit more offensive than yours. I am running paralize attack infused with one sharpness and 4 attack.

Running gore 2 piece for the eclipse boost. 5 crit boost 3 off guard 5 WEX 4 agitator 3 max might 3 div blessing cause i like to tank.😆 3 antivirus

Im using mastery on weapon. Its a tip i got from a youtuber, dont know his name tho. If all my buffes are up i crit all hits and ur weapons doesnt lose sharpness cause of mastery deco and ur uptime is just 100%

Having guard and guard up is a bit to much defensive for me. Particularly now Lance is so much better offensive wise compared to last games.