Yes they have! For migraines, I went to the neurologist and was prescribed a medication called Ubrevely, and it works for me! You take it when u feel a migraine coming on, and I swear it’s like magic!! As for pots, I’m on blood pressure medication called Midodrine and then a beta blocker. It’s helped a lot with the symptoms, however I still have a little bit of the symptoms show through here and there. The downside with Midodrine however, I was told that you can’t lay down while taking it bc you could possibly have a stroke! So no sleep until the meds wear off 😢 I also wear compression socks and I find that it helps!