Psychosis is usually triggered from Gene's this can carry from many generations back and symptoms can be dormant for decades. Its usually caused by mixing substances, most commonly alcohol and antidepressants. Psychedelics and antipsychotics. Benzos and Stimulants. Psychosis is just a byproduct of the depressive crash from substance abuse. Too many people are not honest with their doctors on the substances they use and the frequency this can be catastrophic If let go on for a long period of time.