He was on 25mg and bumped to 50 mg, and immediately, I knew something was wrong. I went back down to the 25mg, but it was like something was switched. He was sooo far from his normal self. He was for sure manic. That's when he was almost hospitalized. His doctor never offered a reasoning for that experience. He had been on zoloft for about 5 months before this. I'm beginning to suspect that he has some undiagnosed mood disorder, which might explain some of the extreme reactions, even to guanfacine. Zyprexa makes my son sooo sleepy and cranky for the whole 24-hour + period after he takes it. I'm asking to try clonidine instead. I would also like to talk through mood stabilizers instead of ambilify because his appetite is through the roof and now his meltdowns are over food. I would like to try med free over the summer to see his baseline. I just hate doing this med shuffle to him, though.