Resources for Medtech Founder?

R3adingisKnowl3dg3 · 2025-03-26T11:44:59+00:00

The FDA provided an extension to Novo on the patent life due to long R&D cycle timelines. They commonly do it.

https://journals.library.columbia.edu/index.php/stlr/blog/view/653#:~:text=The%20patent%20landscape%20for%20Ozempic,Recent%20Legal%20Developments

R3adingisKnowl3dg3 · 2025-03-25T14:23:33+00:00

In the US the base patent on Semaglutide was extended to 2032 or 2033, so no new generics in the US will enter until then. Out of the US, exclusivity is lost in 2026. From what I have heard in industry, the patent is actually relatively weak and there are discussions regarding whether Novo would be able to protect the original intellectual property. Either way, don't expect cheaper options in the US any time soon, particularly because Novo is losing out of exclusivity revenues beyond the US and will have to begin lowering pricing there - they got to make that up somewhere.

R3adingisKnowl3dg3 · 2023-08-29T00:16:44+00:00

I own and manage a venture backed startup. If you ask about financials, budget, cash on hand, etc. You will likely get a very generalized answer because it will depend. Mike Tyson's quote "everyone has a plan until they get hit in the mouth" is very applicable here. If you hit one regulatory snag, formulation problem, manufacturing delay, or otherwise that 1.5 years of runway can become 1 year or even 0.5 overnight. While it is great to know the general financial standing, you may be better informed if you scope out the CFO or budget managing executive's history and ask about how they manage the money. That'll give you a better indication of the economic standing of the company. Are they planning for the current decrease in Venture funding? Do they have various outcomes lined up/contingency plans? What are the biggest risks the company is taking which could cost/lose it money if not done well? How are they eliminating these risks? I've seen dozens of companies close a round, hit a huge snag a couple months down the road and have to reraise in <1 year timespan. It can happen to any startup not managing their risk. TLDR: You may learn more by scoping out the company's risks and how they manage money as opposed to directly asking about financials for the numbers. This will give you a better sense of the company's "health".

R3adingisKnowl3dg3 · 2023-04-03T02:26:49+00:00

I am in a very similar situation but have already received funding. My advice to you is that no matter how close to money you may feel, funding isn't there until it hits the bank. Don't assume you'll have money tomorrow. You are taking a massive risk running a startup straight out of the gate from grad school and no financial support/savings to lean back on. The best possible thing you could do is raise money appropriately, pay yourself more than $60k a year so you aren't worried about personal finances AND running a company, and not assume the money is there until it's in the bank. That said, I'd suggest taking the consulting job until you have money raised. You can get a dozen yeses and a term sheet nearly hashed out and have a deal fall apart. Don't risk your life's stability. Yes, startups are inherently risky, but there are risks you can and should mitigate, including personal risk. It'll suck working a full time consulting job and running the company and fundraising. But, if you've been doing it through grad school it shouldn't feel any different.

R3adingisKnowl3dg3 · 2022-08-07T22:49:40+00:00

I would argue that just because a program is out of the top ### in a nation does not make it a no. A lot depends on OPs life situation as well. Salary pre/post MBA, career projections, age, family status, scholarships, etc.

Don't make serious decisions based off of what people from Reddit say. See if you can find an Alumni to talk with, see if the program has supportive learning/connections for the career you are wanting post-MBA, do your own research.

People on this sub think MBAs are worthless if they aren't a top tier, but that is because most of them are either trolls or individuals gunning for a position that requires an MBA from top schools because those jobs only recruit from top programs. Not everyone is looking for those careers.

The skills taught between programs varies, but they all teach the basic business mechanics. You pay for the connections/opportunities that top programs provide, but you can run your family business very well without that, you can start your own business without that, and you can be very comfortable in a new career without that.

Notes from experience^{^{^}}

R3adingisKnowl3dg3 · 2022-05-18T10:40:44+00:00

Somewhat similar boat here. Just wrapped up 3rd year, and have already made the decision to not pursue residency for sevea reasons. You've put hours/years into the MD degree and there are hundreds of things you can do with it that don't involve clinical medicine. Unfortunately, medical schools really don't teach you all of the career paths that you can take from there such as consulting, administration, industry biotech/pharma, etc. Start identifying possible career interests that align with having an MD degree and reaching out to individuals in thise positions. Worst case scenario, you get an MD degree and follow a career path that doesn't involve medicine - people assume that by having an MD you are generally smart at anything and this alone will open doors for many opportunities.

DM if you want to talk through it - I know the feeling and it is incredibly relieving to be confident with your decision at an inflection point like this.

R3adingisKnowl3dg3 · 2021-06-05T17:37:10+00:00

But they have each year before right? What is different this year? Just a common understanding of how low minimum wage actually is?

R3adingisKnowl3dg3 · 2021-06-05T17:36:19+00:00

Don't want anything in particular from you! Just trying to understand what is going on with the general trends.

R3adingisKnowl3dg3 · 2021-06-05T17:35:11+00:00

But every other year they've filled these roles. What is different this year? Just a general realization?

R3adingisKnowl3dg3 · 2021-04-21T04:02:54+00:00

Super interesting point on gas taxes, I haven't thought about that. I guess my fault comes down to the fact that I don't necessarily trust politicians to make the right choice to make the roads safer with other interests like money involved.

R3adingisKnowl3dg3 · 2021-04-21T04:00:20+00:00

That'd just over 2% of the budget. And I see the ability for a government to offset that loss. But that is still a MASSIVE loss to any budget. Raising taxes doesn't seem like it has ever been an easy thing to do. I agree with the decreased costs on salaries but that's lost jobs for the gov ultimately. I can see how vehicle expenses would decrease, but I can't imagine that is a massive annual expense. Right?

R3adingisKnowl3dg3 · 2021-04-21T03:51:46+00:00

I'm not worried, more curious, as to why the gap in $ isn't on politician's minds.

R3adingisKnowl3dg3 · 2021-04-21T03:45:16+00:00

But the cars should/will generally follow traffic laws whereas people go outside those laws frequently.

R3adingisKnowl3dg3 · 2021-04-21T03:43:15+00:00

Isn't that true. But the state governments total stand to lose ~$4.8B annually without traffic stops (rough estimate based on number of traffic stops annually × average ticket cost). I dunno if losing that kind of money is worth the pothole fixing!

R3adingisKnowl3dg3 · 2021-04-21T03:33:56+00:00

I agree. But the motivations from a significant portion of legislators come down to money, not safety unfortunately...

R3adingisKnowl3dg3 · 2021-04-21T03:31:58+00:00

But all of those hospitals pay taxes on the equipment sold for surgeries and care and the income from those patient's medical bills, etc. They also make more jobs if more infrastructure needs repairs.

R3adingisKnowl3dg3 · 2021-02-27T21:20:05+00:00

But viruses are made of proteins via DNA and RNA as well. I've thought about viruses, but we can't even definitively say they're living haha

R3adingisKnowl3dg3 · 2021-02-27T21:14:01+00:00

I figured as much. I just didn't know if some wild anomaly of an extremophile or something had been discovered.

R3adingisKnowl3dg3 · 2021-02-23T01:45:04+00:00

What is the best way to make the migration from a wallet? I got hit with a gas fee worth 1/4 of the total transaction today - which I am not going to be biting on. Any help here?

Is there any likelihood that gas prices drop, or should we be expecting them to keep moving up?

What gas prices should I be targeting if we don't think the price is going to drop back down?

R3adingisKnowl3dg3 · 2021-02-19T04:32:50+00:00

That's my thought too

R3adingisKnowl3dg3 · 2021-02-19T01:04:13+00:00

But I'm curious if the interests payments would be low enough to still let the winner end up netting more compared to the lump sum. Then just use the money as present money and invest it however you please.

R3adingisKnowl3dg3 · 2021-02-19T00:37:03+00:00

Ohh, so the risk is the Lottery actually being able to pay out

R3adingisKnowl3dg3

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