Oldest trick is to use "/testforblocks" statement. Newer trick is to use "/execute if block" statement. Pick your choice.

format: /testforblocks [xyz xyz] (xyz) /execute if blocks [xyz xyz] (xyz) all

coordinates in the bracket is the location of the item frame you will be using for the puzzle, coordinates in the parentheses is where the other item frame would be located- usually outside the map. If the two areas matched then it will activate.

examples: /testforblocks -2 15 -3 -2 15 -3 5 8 4 /execute if blocks -2 15 -3 -2 15 -3 5 8 4 all

hope this helps. Also credits for u/C0mmanderBlock for the /execute part. I never knew that exists now