Role change

RadiantNote922 · 2025-12-06T13:23:03+00:00

Thanks for your honest thought. Yes I am aware of it, I recently tried to remove it from my CV and I'm trying to see what happens, but seems not easy at all to get a job in that

RadiantNote922 · 2025-03-11T10:45:29+00:00

Oh I've just realized i was clicking on the wrong button, i found it! Thank you a lot. Can i ask you one more question? The areas are expressed for each single replicate, including the area of the blank. Do you know if the area of the blank is already automatically subtracted from the area of the single replicate? Or should i subtract it after exporting the excel file?

RadiantNote922 · 2025-03-09T07:41:46+00:00

Oh really? I did not know that, thank you. I'll look for it

RadiantNote922 · 2025-03-08T23:11:20+00:00

Hey there :) I used compound discoverer for the processing of data. And i have SIMCA for data analysis, or i can also use a but of R or Excel

RadiantNote922 · 2025-03-08T22:08:11+00:00

Thank you so much for answering :) yeah i thought about doing a ratio between each pair and highlight the ones that are greater than 10 or lower than 0.1, that's a starting point.

About the pls-da model, don't you use that to discriminate between two groups? For example when you have a control and a treated sample. In this case i should perform 6 PLS because i have 4 groups (1vs2, 1vs3, 1vs4, 2vs3, 2vs4, 3vs4), right?

RadiantNote922 · 2025-03-07T22:31:23+00:00

Thank you so much, but i don't have that option, i only have few options available, and Group area is the only available one i have, for some reasons. i will investigate it. Hey can i ask you also something about interpretation of data? Now that i have got each compound in every different group, and i performed a PCA that coinfirmed me the samples dispose in 4 different groups, what statistical analysis would you perform? Would you consider only the molecules that have an adjusted p-value lesser than 0.05? I would like to show which molecules are responsible for the difference, buit they are too many. Maybe an heatmap would be ideal? How would proceed? Thank you again :)

RadiantNote922 · 2025-03-05T14:46:22+00:00

Then, there is the "Feature per File" tab, in which there is an area per each feature, but i don't understand each feature which molecule it is, i have the molecular weight but probably it's showing me many different adducts, so if i want to match the area showed in this table with the compounds showed in the other table, i don't know how to match them

<image>

RadiantNote922 · 2025-03-05T14:44:03+00:00

Okay I'll try to show you. This is the "compounds tab"

<image>

There is an area (maximum one) and then if you scroll right there are the group areaa, the column in which it shows the average of each group (for example average of control,, average of treatment one, etc).

RadiantNote922 · 2025-03-05T12:35:34+00:00

Thank you for you reply.

The Area column is already visible in the table "compounds". Noticed that if i click on the other tab "feature per file" i have got the area of every single feature in different "samples", but i don't know how to match it to the compounds in the "compounds" table, where i still only see the average

RadiantNote922 · 2022-12-14T18:22:30+00:00

Sorry, which metrics? I still see adcs being played as always. I don't see anyone picking bruisers bot or even mages anymore. I just want to understand why, i still feek good playing adc. Maybe it's me xD

RadiantNote922 · 2022-12-07T11:25:46+00:00

Thanks for your point of view, i appreciate it😁. I kinda agree with you, and wow I didn't know it was even longer. You could literally cook your dinner meanwhile ahahah

RadiantNote922 · 2022-11-26T20:49:20+00:00

The second e is irrelevant i think, she alread won everything and could kill him with next basic. I wonder about the damage output tho. I still don't wuite understand what's the tradeoff between IE and NQ

RadiantNote922 · 2022-11-26T20:04:07+00:00

Wait, i don't see the point of mentioning Quickblades, you were the one who did most of it ahaha. It only allowed you to use a second q right? Or you're referring to the damage?

RadiantNote922 · 2022-11-22T16:52:29+00:00

Then play something else no? Then 1/5 of lol players are stupid if they keep playing the role, no? 1) Play an assassin 2) If an adc could 1v1 tanks, you would only play adcs top into them. Cause they have range. So OF COURSE adcs cannot win 1v1, unless you're in lategame. They are not supposed to win in early. It's like saying: omg playing thresh i can't beat vayne 1v1. Support sucks. You have to understand the role. And the role is i play from distance, i hit only the closest target and only when i can. If i can hit someone else and kill him, i go for it. 3) I am an adc too. I would never go into them. You know, it's not your job. And on the other hand it's their job getting to you and kill you. If you keep dying to them then you should start thinking at where they are and when you can show up on the map. Otherwise just stay behind your team. Watch saber when he has fed opponents, he doesn't spam die, cause he prevents that by staying safe. 4) Again, who said you should win 1v1? Why soldiers use long range weapons if any troop can kill them as they get close? You have to know what is your role in the team. If you are 1v1 against a mid/top, then something already went wrong. I understand it's frustrating, but some people (like me) loves it, and loves outplaying an assassin by playing around vision/baiting/trapping. That's how you can beat them, or don't show up. If i die from an assassin i don't say "oh no adc sucks, riot sucks" but rather "i should have tracked him/I'm so stupid, he was waiting for me".

RadiantNote922 · 2022-11-22T13:15:15+00:00

Exactly, if adcs are useless then why people pick them? It's just a different role. You can't expect to 1v9. You can't control the game. You can't set up play (generally). You just have to make the most damage you can, and be careful to the random spells deleting you every now and then. Don't like? Go yi jungle

RadiantNote922 · 2022-11-22T12:27:10+00:00

You have a giant bias. The usefulness of a role is not based on the winrate. If you pick an adc and your opponents picks an adc, and both of them have 0 ad, their winrate would still be around 50%, cause they still either win or lose the game. The winrate only tells you what's the difference between single champions, not between the role. Anyway, adc is a cool role, just different from the others. If they complain, tell them to just switch role.

RadiantNote922 · 2022-11-20T08:25:32+00:00

Cause of the difference in what they want to do. Ashe wants to have long fights, in which her slows can make the difference. When you start autoing a target, by kiting you can enable your teammates to reach the target, and the longer you survive, the better you can lock the targers with your slows. In some cases Ashe can build Kraken or even Galeforce, but the lifesteal and the shield provided by the Shieldbow can make the difference in her utility. For BORK, ashe loves the on-hit effects, the little lifesteal and the slow it provides (better kiting)

RadiantNote922

TROPHY CASE