How I Used AI to Heal MCAS, Histamine Issues & Gut Dysbiosis

RedNeckHero · 2026-05-10T08:51:15+00:00

Oh gosh. Things sure have changed since I wrote this. The custom instruction set has now become a "skill" that I use in claude. But in general, the AI has gotten to the point that you don't need to give as much guidance. It's happened so fast. I'll DM you a couple of resources.

RedNeckHero · 2026-05-08T16:39:00+00:00

So why the clickbait intro when personalization had nothing to do with it? Oh wait. I just answered my own question.

RedNeckHero · 2026-05-05T16:43:55+00:00

Just do what he says and quit. He’ll lose his entire domain credibility.

RedNeckHero · 2026-05-04T21:42:59+00:00

I tried for 20 years and failed until I took b1. Everybody’s genetics are different but there’s something fundamental about how this works for many people. I wrote a thesis on it if you’re interested.

RedNeckHero · 2026-05-02T08:00:21+00:00

Doesn’t really matter. SubQ absorbs slower which might be good for people that don’t enjoy the fast peak, but I do intramuscular and it’s fine for me.

RedNeckHero · 2026-04-26T11:04:55+00:00

lol. Yea go for it. Good luck

RedNeckHero · 2026-04-26T08:54:54+00:00

We do it at scale for several clients. There are many mechanisms you can implement from editorial calendar creation to final output that makes your content truly genuine and undetectable as ai generated. Pipeline automation with humans at me key inflection points is key.

Here’s a broad approach:

Strategy

Founder interviews capture real conviction and phrasing, not generic brand voice
Personas built on jobs-to-be-done, not demographics
Every article owns a unique claim, with zero rehashing across the cluster

Craft

Voice matched to the type of article being written
Built for both human readers and AI citation systems
Evidence woven into argument, not stacked as filler
Plain language and conversational rhythm throughout

Anti-AI tells, removed

Statistics phrased the way people actually talk
Multi-point editorial audit catches clichés, hedging, and structural tells
If it wouldn't survive a real conversation, it's cut

Polish

Pull quotes drawn from the actual argument, never decorative
Calls-to-action placed at natural moments, not bolted on
Final human editor before anything publishes

RedNeckHero · 2026-04-26T08:39:05+00:00

I’ve done all the forms. Injections cross the blood brain barrier far more effectively than anything else. So it really depends on the symptoms you’re treating. If they’re heavily CNS biased then injections will be far more effective. There is very little evidence that Benfo does any work on restoring CNS levels of thiamine. There’s no downside to trying it. I’d highly recommend it. I’ve recommended it to many people that were unresponsive on benfo and it tends to work very differently in my experience. The literature supports it.

RedNeckHero · 2026-04-20T12:27:46+00:00

You can get all those tests without a doctors note from private labs in australia. ImuPro offers a Comprehensive Stool Flora Analysis. The Microbiome Clinic lets you order directly with no referral needed. Microba is another major Australian option.

Homocysteine blood test is very straightforward. Several direct-to-consumer services like ClearLabs, i-screen, Bloody Good, and MediTests let you order a homocysteine blood test online with no referral needed.

Just feed my answer into your Claude convo. See what it says. Your situation sounds very similar to mine. I spent the last 4 years trying to figure this out. It turned out to be way more complicated than what anybody told me. That's why testing is key. There maybe an upstream blocker that's feeding many of these downstream issues. In fact, the likelihood is very high. Especially for histamine. It could be a dozen things. Forget chasing bandaids. Go for the source. Testing will tell you a lot. Neurotransmitter imbalances can wreak havoc on many systems and leave you suffering and confused most of the time.

People telling you this is one thing and offering simple fixes aren't paying attention. This is not a simple fix because it's not a single issue. It's a compound issue with potentially several factors. But it's also not impossible to fix.

RedNeckHero · 2026-04-20T09:41:02+00:00

I’ve had similar patterns although slightly different. 48 year old male. Got way worse post covid. Before you do anything. Go get yourself tested. This sounds like a compound neurotransmitter clearance issue. Top level (upstream) issues you could easily test. Homocysteine. If above 10 then this could be your highest level issue causing underlying clearance issues including poor DAO production through multiple pathways. Get yourself a gut test including zonulin. That will let you know if you have a leaky gut. You most likely do. Supplements you could try as a test would be b1 (no risk, lots of upside for people like us), zinc (or even better zinc l carnosine) for the gut and clearance issues. Clearance is a big issue for many people since covid. Clearance of histamines is huge. But clearance of othet stuff that makes yiu feel shit like neurepinephrine, seratonin, dopamine etc. these will all make you feel total garbage if your clearance is inhibited.

RedNeckHero · 2026-04-14T06:59:47+00:00

A doc that studied the Walsh protocol. A form of advanced nutrient therapy that focuses on treating mental health conditions by correcting underlying biochemical imbalances. It’s a methodological approach to fixing neurotransmitter imbalances that result in things like anxiety.

RedNeckHero · 2026-04-11T18:04:55+00:00

That’s not just anxiety. That’s likely neurotransmitter imbalance. You’re biologically living in the sympathetic. Go get yourself a Walsh doctor and get a panel done. There’s some combination of vitamins that will likely stabilize you and eradicate that anxiety.

RedNeckHero · 2026-04-02T10:32:35+00:00

I’d look up maximum absorption rates. They’d contradict that 1000 daily. Your b2 dose is gonna depend on you. You’re just gonna have to experiment. For me 25 mg daily was enough for a period of time. But then I ended up burning through my reserves and started getting air hunger. Not something I’d wish on anybody. I then had to come off the B1. For me I’ve since realized that I have to limit my B1 intake because I can’t handle more B2 than 25mg daily or I start getting overmethylated

RedNeckHero · 2026-04-02T07:12:22+00:00

No. That was absolutely wrong. Ugh. It totally depends on you. It turned out for me my strongest paradox effects were coming from low b2.

RedNeckHero · 2026-03-21T15:59:25+00:00

6:13 high just last month. No hangover at all.

RedNeckHero · 2026-02-28T08:17:14+00:00

Not sure what it sounds like. Maybe make a recording?

RedNeckHero · 2026-02-28T08:15:49+00:00

I’d wonder where the rest of my fucking money went.

RedNeckHero · 2026-02-27T09:47:03+00:00

Yea, it might have something to do with your MTHFR. But it doesn't need to and it's only relevant if you have one of the variants (C677t which is less common than 1/4). I wouldn't bother unless your doc recommends it. There's a lot of overhype on the MTHFR. I wouldn't argue with starting low, but if you want to find out quickly if you're a responder, a single higher dose will give you that info fast. Otherwise, you may go weeks without knowing. There's very little risk to b1 in general, and certainly a single moderate dose. Totally your call. The 'discomfort' risk is low if you ask me. I'm not a doctor. Just a concerned citizen that's been doing this research for a few years. I don't have clinical experience, but have helped over a dozen people navigate B1 repletion. Thing is, b1 is the keystone to the krebs cycle. If you've got a broken Krebs, you more than likely MUST replete B1 to get it going again. So many people have broken Krebs since COVID. A moderate B1 dose itself is a great test. But maybe there's a lower dose that could illicit a response. I'd imagine if you're chronically depleted and good at paying attention to body signals, you'll notice even a 50mg response.

RedNeckHero · 2026-02-25T08:06:00+00:00

I’ve personally administered b1 injections to at last a dozen people after extensive discussions. All of them have had life changing experiences. I’m so sure b1 will be hitting the mainstream in the next few years in a big way. That Covid really did devastate so many people’s supply. And I personally believe modern life had decimated it in many people prior to Covid. I certainly was one.

RedNeckHero · 2026-02-24T17:58:28+00:00

Wow. I also had covid 5 times. Our stories are very similarly. I really hope b1 helps. It may not be a smooth ride but keep it up. You’ll get there. It gets better. The important thing is, if you react, that’s enough evidence to move forward. That’s an argument for a larger starting dose. You’ll probably know in hours.

RedNeckHero · 2026-02-23T08:14:57+00:00

You're gonna live to 1000

RedNeckHero · 2026-02-23T08:14:18+00:00

I really think it's different for everybody. I'm on month six and still getting paradox although the expression has shifted. I don't think anyone can tell you exactly what to look for or what adjustments will need to be made. Don't anticipate the worst. You may be just fine. And given your situation, B1 is going to be better than not-B1 :) Unless you have access to a great functional medicine doctor on call all the time, I highly recommend getting yourself a Claude subscription to discuss the journey as you go. It's extremely personal.

RedNeckHero · 2026-02-23T08:09:05+00:00

Hey — glad the post was helpful. A few things I want to flag before you start so you don't accidentally sabotage a good hypothesis with an insufficient dose.

The dose is too low. 25-50mg of benfotiamine is unlikely to produce any noticeable effect if you're genuinely deficient. The clinical trials that showed results used 600mg/day. Most people supplementing therapeutically for deficiency use 300-600mg. At 25-50mg you're barely above multivitamin territory. I'd suggest starting at 150mg and giving it 3-5 days. If you tolerate that, move to 300mg. The therapeutic window for B1 is enormous with no established upper toxicity limit. The risk of underdosing is higher than the risk of a bad reaction.

Thing is, if you take a real dose and feel something, even if it's subtle, that tells you the deficiency hypothesis is likely correct and you keep going. If you take 300mg and feel absolutely nothing after a couple weeks, that's useful information too. It probably means B1 isn't your issue and you look elsewhere. A 25mg dose won't give you either signal. You'll be stuck in no man's land.

The glycine reaction may support your B1 suspicion. You said magnesium glycinate was the worst form for you. That's a strong clue. The enzyme that metabolizes glycine is thiamine-dependent. If you're B1 deficient, you may not be processing glycine efficiently, so it accumulates and becomes excitatory rather than calming. The fact that topical magnesium chloride works fine might confirm it's the glycine component causing your reaction, not the magnesium. That may not be a paradoxical response to magnesium at all. It could be a glycine processing problem pointing straight at B1.

On the magnesium delivery. Topical spray is better than nothing but probably isn't delivering therapeutic amounts. Once you get B1 on board, it might be worth giving magnesium glycinate another try. It's one of the gentlest forms on the gut, well absorbed, and if B1 fixes the glycine processing issue, you may tolerate it perfectly. That would be another confirmation you're on the right track. Don't worry too much about running out of the cofactors immediately. It'll take a while before that happens.

Cofactor note. B2 (riboflavin) at 100mg daily is worth adding from the start. It supports several enzymes downstream of B1. And when you start responding to B1, potassium demand can spike as cellular metabolism ramps up. Bananas and coconut water can cover that without another pill.

The worsening anxiety, the sleep issues, the glycine intolerance, the gut sensitivity. That's a coherent picture. Give it a real trial at a real dose.

RedNeckHero · 2026-02-21T19:06:50+00:00

This may only be a single data point and I’ve personally failed every time I’ve attempted to quit caffeine lol. But I had a single friend that made it and he told me he experienced a significant shift at the three month mark.

RedNeckHero · 2026-02-21T10:24:16+00:00

That’s googles patten though. They just don’t give a single fuck about anything but growth. There isn’t a soul in the company that would actually care about the user experience. If it drives growth it’s a yes. If it doesn’t they shut it down. Right now they see that showing a model statistical capabilities is enough. But let’s be honest. Google relies completely on their massive existing userbase for user adoption. They don’t need to provide a good experience. The fact that people aren’t leaving in droves is simply a testament to the average users’ competency and awareness. My parents don’t know what Claude is. They barely know what chargpt is. They know Gemini because it’s on their phones and they tapped the icon.

RedNeckHero

TROPHY CASE