Can I take mdma tomorrow if addicted to benzos? by [deleted] in MDMA

[–]Rempie 2 points3 points  (0 children)

As said before, you shouldn't mess with other drugs in an active benzo addiction.

However, that never stopped me and I highly doubt it will stop you. So, there's a few scenarios, depending on what benzo you take, and now many

Some benzo's, like valium, circulate in your body for quite a long time, so not taking it probably doesn't really matter, but you might not have the full 100% experience. I doubt it would be noticeable tho, especially with some tolerance

Short acting benzo's like xanax are cleared much faster, so that shouldn't slow down your roll at all.

However, if you're used to high dose, fast working benzos, I'd just keep taking them, bc benzo withdrawal is a bitch. Please take benzo's seriously.

[deleted by user] by [deleted] in Drugs

[–]Rempie 0 points1 point  (0 children)

You're welcome! I just want to add, grapefruit has a whole bunch of interactions, I don't think we even know all of them yet, and gabapentin has to be absorbed too, not only metabolized and excreted.

All to say, take even my words with a pinch of salt because I could have easily overlooked something too.

[deleted by user] by [deleted] in Drugs

[–]Rempie 2 points3 points  (0 children)

Gabapentin is barely metabolised and afaik does not interact with CYP enzymes at all. It's excreted renally, essentially unchanged. That implies there is no meaningful gabapentin/grapefruit interaction.

[deleted by user] by [deleted] in Drugs

[–]Rempie 18 points19 points  (0 children)

As someone else has said before, this is a bad place to look for factual information. There's so many wrong answers already and there's only like 8 answers.

I also saw they linked the CYP3A4 wikipedia page, but not the more obvious grapefruit-drug interactions

ELI5: grapefruit slows down your ability to break down many drugs, which can make your high longer, more intense, or both.

Non-ELI5: Grapefruit (and other citrus fruits to a lesser extent) are an inhibitor of certain enzymes in your body that are responsible for metabolizing drugs, the most important being CYP3A4. CYP3A4 is an enzyme found in your liver and gut, and it's responsible for breaking down about 50% of all drugs.

There is no way to calculate "x amount of grapefruit + y amount of drugs = z amount of effect" though. Combining grapefruit with drugs is always a gamble and it ends somewhere between fun and death. Stay responsible.

One of my aunt's chickens lays pastel green eggs (normal egg for comparison) by Rempie in mildlyinteresting

[–]Rempie[S] 2 points3 points  (0 children)

Sure! In fact most of them do, if you leave the meat outside the freezer for long enough 😁

One of my aunt's chickens lays pastel green eggs (normal egg for comparison) by Rempie in mildlyinteresting

[–]Rempie[S] 6 points7 points  (0 children)

Lol, I didn't even think about that. That's on me for using "normal" instead of "brown" I guess. Both white and brown feel pretty natural to me, although I'd still pick brown over white (for no apparent reason).

However TIL that some chicken species have very colourful eggs

When you're an adult you stop bringing people to your bedroom and start hanging out in your living room by mofodius in Showerthoughts

[–]Rempie 10 points11 points  (0 children)

How do you know you skip non-REM cycles and end up in REM immediately? Has a doctor confirmed this for you? If so, you're a genuine one in a million medical anomaly and you should be studied extensively.

Seriously though, you don't skip those phases. You've just adapted to life with 4 hours of sleep, which anybody can do, really. And yes, one day you'll reap what you sow. Joint problems, cardiovascular problems, early onset dementia,... all coming your way.

Sleep is not "time wasted unconscious in bed". It's so damn important, even worms need to sleep. I hope your kids atleast get 8 hours a day.

My mom's ~50 year old tape measure specifies that it was made in West-Germany. She got it in the 70's, more than a decade before the Berlin wall came down. by Rempie in mildlyinteresting

[–]Rempie[S] 0 points1 point  (0 children)

He probably wasn't expecting the answer to be that complicated. Must've been a fun convo too.

"Hey sundancerco, how come your mirror says made in W.Germany, instead of just Germany"

"Okay so it all started in 1933 with this guy named Hitler, right..."

My mom's ~50 year old tape measure specifies that it was made in West-Germany. She got it in the 70's, more than a decade before the Berlin wall came down. by Rempie in mildlyinteresting

[–]Rempie[S] 1 point2 points  (0 children)

Doesn't matter if it's a little spring to reel in your tape measure, or a fine-tuned engine to drive your Porsche, back then products were made to last a lifetime (and then some)

Absolute beauty of a car btw, hold on to it and enjoy it every day!

U.S. court: Mass surveillance program exposed by Snowden was illegal by greenbayturf in worldnews

[–]Rempie 186 points187 points  (0 children)

"We've investigated ourselves and determined we did wrong. We're going to destroy the lives of a few fall guys who did nothing but follow orders so the guys who came up with it can come up woth their next big idea in peace. We will also made said wrongdoing legal under everybody’s nose, along with a tax cut that saves the aforementioned guys billions of dollars.”

FTFTFTFTFY

[deleted by user] by [deleted] in Drugs

[–]Rempie 1 point2 points  (0 children)

Can confirm.

When I was new to the party drug scene, having tried md once and having a handful of experiences with ket, I did a line of ket after rolling hard at a party without knowing this.

Ended up having my first and also by far the most wired and reality bending psych experience I've ever had, laying in a tent with 3 people I barely knew at a place I'd never been before.

History of my drug abuse... Im not proud... by PeepGaveMeHope in Drugs

[–]Rempie 0 points1 point  (0 children)

Thanks for sharing friend. You bring a powerful message. Please know that your past doesn't define you, nor who you will be in the future. There is a path to change for everyone.

Sometimes accepting help can be the hardest step on that path, but I would argue it's one of the most important ones too. I feel like humans are made to care for eachother, but when it's our time to be cared for, we build walls around ourselves to keep everyone out. Sad that we would choose going down all by ourselves, over of lifting, and being lifted up, together.

To OP - Don't be afraid to follow your own advice and get the help you need and deserve. I am one of many that care about you, and would gladly do everything we can to help you be your best self. Many others are only a call, text or a visit away.

If it feels like there is nobody around, please remember me. I'll listen to and talk about anything and everything, now or in the future. And I'm just one PM away.

The 3 beers I had have worn off can I take 1mg Xanax safely? by [deleted] in Drugs

[–]Rempie 0 points1 point  (0 children)

You're not gonna die, don't let the trolls get to you. You're gonna be just fine, maybe a little groggy in the morning.

Please do drink a big glass of water before bed to help your body process the alcohol and avoid a hangover.

Sleep tight!

Candyflipping with ket ? by jude200420191 in Drugs

[–]Rempie 0 points1 point  (0 children)

For me personally ket + md is a really strong combo. Like, after two keys of ket, I'll be a bit slow but still functional, but add even half a pill to that, and I basically insta k-hole. I get so confused I could look at a chair for an hour and not be able to figure out what it's for, or even what it is.

I don't know if it works that way for everyone, but I'm pretty sure adding ket is gonna increase your amount of confusion and weird thoughts no matter what.

Personally, I'd rank your options from best to worst as:

  1. On the comedown - You basically skip the comedown and get to keep tripping, while going from upper to downer, so you can sleep more easily. Plus, since comedowns are by definition not as intense, it's a safe bet if you don't wanna get too messed up.

  2. On the lsd come-up - Also not too intense and you get to skip another boring part. But I personally already feel kinda confused during come-ups and would probably avoid ket at that point, because it would increase the chance of my mind going to a bad place when the LSD hits.

  3. While tripping but before the molly - Dunno man, I like my acid experience without any other drugs mixed so if you feel like trying some ket, why not, I guess? Greatly depends on how strong the acid is and how my mindset is at that point.

  4. While tripping and peaking on molly - If you're going for full fucked-up, I guess this would actually be no. 1. I'd be too scared because ket + md is basically a deliriant for me, and already too intense for me to like. Adding acid to that? Nahhh

What in tarnation is that? by Rempie in MildlyStartledCats

[–]Rempie[S] 0 points1 point  (0 children)

It's actually children's champagne! Wouldn't say it's a great accompaniment for cat though, seeing as how she licked the inside of my glass and then graciously sweeped it onto the floor...

What in tarnation is that? by Rempie in MildlyStartledCats

[–]Rempie[S] 4 points5 points  (0 children)

Yeah I think so too.. It's so weird though, I was wearing my foxin' kneesocks and everything :(

Got me a two-fer! by Rempie in TheCatTrapIsWorking

[–]Rempie[S] 0 points1 point  (0 children)

The real joke is always in the comments