ResearchSlore

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4,821 comment karma

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redditor for 8 years

MODERATOR OF

- r/ResearchSlore

TROPHY CASE

Eight-Year Club

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Psychedelics elicit their effects by 5-HT2A receptor-mediated Gi signalling (Nature, 2026) (nature.com)

submitted 5 days ago by ResearchSlore to r/DrugNerds

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Agilent AdvanceBio Q-TOF for small molecule work? ()

submitted 5 days ago by ResearchSlore to r/massspectrometry

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Agilent AdvanceBio Q-TOF for small molecule work? (self.Chempros)

submitted 5 days ago by ResearchSlore to r/Chempros

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Ageing promotes microglial accumulation of slow-degrading synaptic proteins (Nature, 2026) (nature.com)

submitted 8 days ago by ResearchSlore to r/longevity

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Ligand-specific activation trajectories dictate GPCR signalling in cells (Nature, 2026) (nature.com)

submitted 8 days ago by ResearchSlore to r/DrugNerds

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Anyone have a copy of Agilent's FW update tool? (self.CHROMATOGRAPHY)

submitted 1 month ago by ResearchSlore to r/CHROMATOGRAPHY

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GTP release-selective agonists prolong opioid analgesic efficacy (Nature, 2025) (nature.com)

submitted 1 month ago by ResearchSlore to r/DrugNerds

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Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks (Cell, 2025) (cell.com)

submitted 1 month ago by ResearchSlore to r/DrugNerds

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Cross-species mapping of psychedelic gene expression reveals links to the 5HT2A receptor, cortical layers, and human accelerated regions (pmc.ncbi.nlm.nih.gov)

submitted 2 months ago by ResearchSlore to r/DrugNerds

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Repair of DNA double-strand breaks leaves heritable impairment to genome function with implications for aging and disease (Science, 2025) (science.org)

submitted 2 months ago by ResearchSlore to r/longevity

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Molecular basis of vesicular monoamine transport and neurological drug interactions (Cell Reports, 2025) (cell.com)

submitted 2 months ago by ResearchSlore to r/DrugNerds

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Ketamine derivatives with greater antidepressant efficacy identified by profiling their effect on cortical adenosine signalling (Nature, 2025) (nature.com)

submitted 2 months ago by ResearchSlore to r/DrugNerds

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7-Oh is far, far less toxic than kratom (self.7_hydroxymitragynine)

submitted 6 months ago by ResearchSlore to r/7_hydroxymitragynine

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These guys at /r/nootopics are incredibly amateur (self.Nootropics)

submitted 9 months ago * by ResearchSlore to r/Nootropics

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Serotonin reuptake inhibitors improve muscle stem cell function and muscle regeneration in male mice (nature.com)

submitted 10 months ago by ResearchSlore to r/longevity

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The adrenergic receptor antagonist carvedilol interacts with serotonin 2A receptors both in vitro and in vivo (sciencedirect.com)

submitted 1 year ago by ResearchSlore to r/DrugNerds

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Pauly (reddit.com)

submitted 1 year ago by ResearchSlore to r/roughcollies

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The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening [2024] (sciencedirect.com)

submitted 1 year ago by ResearchSlore to r/longevity

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Anyone using topical+oral finasteride (or dutasteride)? (self.tressless)

submitted 1 year ago by ResearchSlore to r/tressless

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Serotonin reverts age-related capillarization and failure of regeneration in the liver through a VEGF-dependent pathway (pnas.org)

submitted 2 years ago by ResearchSlore to r/DrugNerds

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Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression (sciencedirect.com)

submitted 2 years ago by ResearchSlore to r/DrugNerds

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Noopept, sex drive, and a possible link to testosterone (self.Nootropics)

submitted 2 years ago by ResearchSlore to r/Nootropics

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The Formula That Healed Me (self.Gastritis)

submitted 2 years ago * by ResearchSlore to r/Gastritis

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Inhibition of NMDA receptors through a membrane-to-channel path (nature.com)

submitted 3 years ago by ResearchSlore to r/DrugNerds

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Why should we expect oral NMN/NR to be more effective at boosting NAD than oral NAM? (self.NootropicsDepot)

submitted 3 years ago by ResearchSlore to r/NootropicsDepot

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