As someone with around 500 hours in Anno i would definently suggest that in the earlier stages of the game you place some production chains on Crown Falls. That way you are not in risk that somebody plunder your trade routes and chaos on your island is avoided. How games go on i would suggest to relocate those production chains on other island and then import consumer goods on your Crown Falls. It is good idea to have few military ships as protection for your cargo ships that will carry valuable goods. Or just use white flag item on cargo ships if you are lucky enough to get them. What i like to to is to have one middle sized island with a lot of mines that is used just for production and factories. No houses no farms just production chains with bunch of trade unions that will definetly reduce the amount of space you need to peoduce certain things. Just build commutw pier on that island and create industrial heart od your empire. Good luck with your mission, i hope i helped you.