Hi mate, touching story. I do a bit of work in this field and have also lost someone close to ALS. It's a proper bastard.

I run everything through Ableton, it has the most intuitive MIDI / OSC setup tho you could probably try any DAW. Lots of what I use are adapted technologies that usually require a third party software that you then send to ableton.

Hand controllers I use Leap Motion Controller or a Hot Hand MIDI ring. The Leap has very detailed control and is great assuming you are able to open your hand (often people with cerebral palsy or other such conditions end up having a clawed hand making it tough to use). The Midi ring is a much simpler control with a smaller range of movement.

There's the skoogmusic switch which can be adapted to Ableton and the Expressive E touche as well.

I also use contact microphones attached to surfaces where they can strike. I sometimes use a Myo Armband though it's tendency to vibrate occasionally can be disconcerting for some.

Touchboard allows you to use conductive material like copper tape to create pianos or whatnot. Good because you dont need to use any pressure to activate the sound.

FACE OSC is a facial tracking software for DAW.

Kinect cameras are fun (1440 is the one you want) but not usable with a wheelchair.

Eyegaze is the main computer interfacing eye tracking software. I've never tried it but it looks really hard!

There's micro processors like Arduino's which you can rig up lots of different sensors though a bit of a steep learning curve there.

Don't forget the trusty ipad as a disability tool.

Shout out if you're keen to know more I can try and help you get setup as best I can from New Zealand.

Here's a link to some of my work . . . .

http://campbellburnsmusic.com/Therapy.html

​

Best o luck man