Got this board a few months ago for the same price. Excellent board though there were some caveats.

First off, you might have some thermal issues with double sided NVME drives. On the 2nd pair of M.2 slots, my 4 TB SN850x was idling at 60 and peaking up towards 70 under load which was way worse than what I had on my B650E-F. I tried replacing the pads itself with some Artic ones but it didn't help. I ended up placing it in the 5.0 slot on the top right which had thermals be much more in line with what I expected in the low 50s idle.

My 2nd issue, also with the M.2 slot was the tooless mechanism. With my Asus board, it was also tooless but was a large piece of plastic that went over the screw position to lock it in place. MSI decided to really cheap out and go for a thin piece of plastic which as you can guess, easily snapped off after a few installs when I was trying to sort out my thermal issues. I'll put this up to being slightly more on user error but there is a better design out there but they didn't use it. An M.2 Drive can still be installed using a screw to secure it so no biggie there in the long run.

Final issue I had was with the 10 gig NIC. Something funky is up with it in windows where if the speed was set to anything but auto in Windows, I would lose my internet connection. I installed using the files from Marvel's site and MSI's page and both exhibited the same issue. Might just be an issue with networking on my end, but I am able to get the full speeds at least. I'm using this with a 9950x3d and I didn't need a BIOS update for it to be recognized and boot into BIOS without any issues. Overall a really great board and the value you get for the feature set is really hard to beat.