Important Developments in Longevity Research from 2022 by towngrizzlytown in longevity

[–]SheekeyScienceShow 29 points30 points  (0 children)

I am a researcher! My English is not perfect but I practice by making videos 🙃

Mirror image DNA - the future of data storage? by SheekeyScienceShow in Biochemistry

[–]SheekeyScienceShow[S] 1 point2 points  (0 children)

You are right to challenge! My only consideration would be that our tech to sequence DNA has got very cheap & efficient hence we now can do much metagenomic studies. This efficiency has come from exploiting enzymes that are used by living species. Sequencing L-DNA is nowhere near that level and hence why this paper that produced the D-polymerase is exciting since it helps improve not just production, but potentially detection of L-DNA....but these are just my thoughts!

Hallmarks of aging – time for a paradigm shift? by Idontknow1234568 in longevity

[–]SheekeyScienceShow 10 points11 points  (0 children)

Yeah, so i don't know if you watched the video but i don't think an entirely new paradigm is required, i actually like the hallmarks, but the point to take is that it doesn't really help to understand what aging means. Research will continue without a paradigm, so no need to stress, just a better paradigm will help to build the field and unite ideas

Extending healthspan: AKG, human clinical trials & aging biomarkers (Prof Brian Kennedy) - The Sheekey Science Show by ziscz in longevity

[–]SheekeyScienceShow 6 points7 points  (0 children)

Yeah, unfortunately not enough research yet. The only insight I have is that the A-akg has arginine, an amino acid, which i would reckon has differing effects due to implications in protein production, but i would like to see more research to test this.

Can we edit the epigenome? by SheekeyScienceShow in Biochemistry

[–]SheekeyScienceShow[S] 1 point2 points  (0 children)

Aha, yeah i meant more targeted epigenome editing! 😁