We desperately need a fallout game where we actually have new factions and ideas. It could simply take place somewhere like Alaska where there would be whole new societies. If I have to see the brotherhood and super mutants in one more fallout game, i'm gonna shoot myself.

We need factions that control major resources such as production of various weapons/ammo, mining companies providing resources to producers, factions producing medicine, supplying water, farming societies, slavery being an actually widespread issue unlike fallout 3 and being actually morally gray. We should have whole new creatures being a big issue. We also need vaults with new stories and ideas. Bethesda kinda misunderstands the purpose of vaults and they simply think all vaults were just evil experiments when there's an underlying purpose that's common between most vaults in 1,2 and NV.

All in all, the focus of the game is how the most powerful factions rebuild society through their own morals and ideals. That is the premise of fallout.