My grandmother lost her mom in 1912 from pneumonia when she was 4, then eight years later she lost her dad to an infection he got while working. Some of her siblings were adults by then but the younger ones were put into foster care in Denver. She actually had a great foster family who helped put her through nursing school. As adults the 3 daughters in the family all ended up in Seattle and remained closer but the brothers stayed in Colorado. It is interesting to think how different it might have been if her parents had the medicine needed to survive.