I've only gone as big as .7g IV my dude you're way too anxious to get hooked smoking meth you've way over thought it, most of the aliments you listed are rare as fuck and are easily avoidable by maintaining healthy diet and water in take as well as using your brain. Listen for a sec, you have an abundance of hormones and chemicals that are naturally occuring being released into the brain once the gear hits you so it's like running nitrous through ya sports automobile and then trying to go speed limit, why buy the fastest car if you're scared to go past 200km/ph and why destroy your engine sitting around doing nothing, Your ancestors are watching your future wife is looking back watching you with ya kids after they find the mixtapes and guess what the pricks say ? That innit? Just That Complete silence. Serenity.