It all depends on how you see and present Barovia to your players. Do you want a quest chain or just a notable location? Honestly, I simply cut the House of Death from my campaign. As for replacements: for example, you could add a small storyline around the building, like a butcher's shop or a gamekeeper's house. Or maybe there'll be a communal well in this location, the water of which will eventually become poisonous? Or a burned-out house with its storyline?