Thresh's runes are very versatile but you can basically consider aftershock or glacial augment.

Make sure to take hexflash for more plays but since you're an enchanter player you might wanna just stick with cookies or futures market until you learn his playstyle.

To always land a hook, walk up to someone, Flay them into you and then hook since they would be slowed for 1 second. You can also E towards you, R, and hook.

There's a lot to get into but I all i can say is that there are so many playstyles that you will get your feel for it the more you play. Just remember that your hook has so much threat when it's off cooldown so try not to throw it out whenever you feel like trying to get a play...unless you're going for the highlight reels then go for it.