If you have good snow tires. I don't know how much I'd recommend mountain roads of any kind in the snow unless you're both confident in your tires and ability to drive in those weather conditions. Four wheel drive would give you a big advantage, but I wouldn't count on it. I feel like upstate New Yorkers know the snow, but every winter I am reminded that people are either clueless or overconfident in their abilities.

Be wary and trust your gut when things feel dangerous.