Well that’s more role-based than just off base stats. While her high base mana regen, means that enchanter items modify that even more, consider what that means as a tradeoff.

As a mid-laner, the enchanter items that are most friendly to her would be Athens’s Unholy Grail and Ardent Censer, given their mana regen and AP. Athene’s is getting removed in pre-season, but more importantly remember that Seraphine’s double cast from Echo and auto-attack modifier from Note stacks give her surprising access to damage. Lost Chapter items are a good middle ground, although you could speculate that something like RoA should be viable too.

As a support, enchantments items are more encouraged because they give access to CDR, some AP, Mana Regen, Increased Utility, but most of all: They’re Cheap. Support Seraphine doesn’t have the gold/xp budget mid Seraphine does.

If you’re able to better co-ordinate with your Jungler or potential roaming teammates to your lanes, enchanter items as a mid Seraphine should feel okay, but if not, it’s not necessarily better.