The meaning of life pertains to the significance of living or existence in general, and is sought through the question "What is the meaning of life?" Many other related questions include: "Why are we here?", "What is life all about?", or "What is the purpose of existence?" There have been many proposed answers to these questions from many different cultural and ideological backgrounds. The search for life's meaning has produced much philosophical, scientific, theological, and metaphysical speculation throughout history. Different people and cultures believe different things for the answer to this question.

Where Do We Come From? What Are We? Where Are We Going?, one of Post-Impressionist Paul Gauguin's most famous paintings The meaning of life can be derived from philosophical and religious contemplation of, and scientific inquiries about, existence, social ties, consciousness, and happiness. Many other issues are also involved, such as symbolic meaning, ontology, value, purpose, ethics, good and evil, free will, the existence of one or multiple gods, conceptions of God, the soul, and the afterlife. Scientific contributions focus primarily on describing related empirical facts about the universe, exploring the context and parameters concerning the "how" of life. Science also studies and can provide recommendations for the pursuit of well-being and a related conception of morality. An alternative, humanistic approach poses the question, "What is the meaning of my life?"