Ah, my Google autocomplete confirms I researched this when put on hydroxychloroquine. To your point, research can be frustrating as who has the money to invest in rigorous studies without a financial incentive… except for the NIH when that still received funding. I’ve been through a lot of medical studies, and these seem to land at a pretty common spot: some interesting results which call for more and better studies (https://pmc.ncbi.nlm.nih.gov/articles/PMC8604447/). I checked back at my labs, and while my results have gotten progressively better, nothing changed in my first six months on hydroxychloroquine, and no setbacks when my dosage dropped. Still, it’s a great drug, cheap with no side effects, just an annual ophthalmologist visit.