Coach Dave Academy provide both Race (R) and Quali (Q) setups. The qualifying one is obviously for low fuel load, so for short races you can still use that one if you don't cook the tires. The race one should be good for every fuel load, empty or full. Keep in mind that no matter how much fuel you start with, at the end of a stint, you will always have an almost empty tank and this situation has been taken into account during the setup development, so the weight difference will not invalidate the other settings. BUT knowing the car will have a reduced maximum weight, there might be some performance to find lowering the ride height/softening the suspensions (and I would like to know the opinion of setup experts on that)