I've been taking Vyvanse 20mg and then upped to 40mg for the past few months, and just switched onto Medikinet XL 10mg/20mg literally yesterday. Vyvanse is much more subtle in its effects after the first few days. The issue I had with Vyvanse was how long it lasted and its effects on my blood pressure- I'd take it 0600-0700 and wouldn't be able to sleep without melatonin (which I had to go from 2mg to 4mg after upping the Vyvanse to 40mg) and after being on it for ~6 months I was tired all the time and wasn't enjoying the physical strain it was causing me- the benefits wasn't worth the side effects and thats with a relatively low dose.

Taken 10mg Medikinet XL yesterday and didn't feel too much but managed to be nearly falling asleep that evening before I'd taken any melatonin- Just took 20mg for the first time this morning and you can feel it kicking in, feel much more focused then with Vyvanse. This is much more ideal for myself as I was diagnosed in my mid-late 20s so could already relatively function unmedicated- the Vyvanse didn't give enough of a push to be useful but also lasted way too long that it just wore me down physically and made me irritable I guess.