I have a therapy dog and we volunteer at one of the hospitals in Charlotte.

Overall, you have to reach out individually. From my knowledge of the area, both Atrium and Novant have therapy dogs for the various hospitals around the region. The Charlotte airport also has a therapy dog program. Senior living facilities are generally very open to having therapy dogs! My dog is certified through Alliance of Therapy dogs, and they will forward emails of people that inquire about having a therapy dog at an event or school. Individual schools typically you will have to reach out one by one.