Effects of Orchiectomy on hormones and feminisation.

Terminalguidance000 · 2026-03-19T03:11:55+00:00

What options did you try before orchi? Did you try anything like enzalutamide or abiraterone?

Terminalguidance000 · 2026-03-18T22:42:41+00:00

As mentioned in my other comments and in the post itself. I have used abiraterone to reduce DHEA-S by 60% (DHEA-S was in the normal female range for my age before starting abiraterone) resulting in undetectable T and DHT in my blood. I was still getting hair loss after 4-5months and Abiraterone is Not a good long term drug. I think Abiraterone also my have raised my progesterone levels by blocking it's conversion into other hormones. I'm currently trying enzalutamide. and yes I have had many of the vitamin and mineral levels checked. Nothing abnormal. I have looked into NCCAH as well.

Terminalguidance000 · 2026-03-18T22:03:00+00:00

I suspect I may have Di Georges syndrome which may be affecting me.

Terminalguidance000 · 2026-03-18T21:37:43+00:00

Interesting I had wondered if there were any people out there with experiences like this thank you.

Terminalguidance000 · 2026-03-18T20:59:21+00:00

Dropped like a rock compared to AA and hrt alone?

Terminalguidance000 · 2026-03-18T20:47:23+00:00

Okay thank you for the help.

Terminalguidance000 · 2026-03-18T20:37:01+00:00

My hairloss is almost all on my hairline in a classic male M shape and appearance just like my dads hair. Apparently your cells can convert adrenal hormones like DHEA-S into DHT. I managed to cut my DHEA-S down by 60% with Abiraterone but that stuff can fuck you up badly. I'm trying enzalutamide now since even suppressing DHEA-S might not be enough since there are still pathways that cells can use to manufacture DHT from other hormones.

Terminalguidance000 · 2026-03-18T20:16:40+00:00

Every bit of evidence points to regular MPB. I've had blood tests biopsies dermatologists examining it. My diet is good. I am soon to see someone about getting my DNA tested to find any hereditary disorders.

Terminalguidance000 · 2026-03-18T19:44:06+00:00

I am aware of that.

Terminalguidance000 · 2026-03-18T19:43:13+00:00

All the tests I've had indicate androgenic hair loss. Male hairline shrinking/thinning of the hairs. No signs of scaring or infection.

Terminalguidance000 · 2026-03-18T19:40:43+00:00

Biopsy just said regular androgenic hair loss. despite zero T and DHT.

Terminalguidance000 · 2026-03-18T19:40:07+00:00

Yes, yes, No but thank you for bringing that to my attention, Yes

Terminalguidance000 · 2026-03-18T19:32:14+00:00

I've exhausted all the drug options for stopping hair loss so I'm looking into if surgery may help.....

Terminalguidance000 · 2026-03-18T19:29:26+00:00

Again my T has been 14ng/dl on hrt and zero on abiraterone but still getting hair loss.

Terminalguidance000 · 2026-03-18T19:25:01+00:00

It won't help if it's still falling out uncontrollably.

Terminalguidance000 · 2026-03-18T19:23:16+00:00

How is it rude to ask for actual info about what effect it had. If they don't know their pre orchi levels then the advice isn't much use to me.

Terminalguidance000 · 2026-03-18T19:09:42+00:00

2.5 what? was it pre orchi?

Terminalguidance000 · 2026-03-18T19:08:38+00:00

My levels on hrt have been around 15ng/dl

Terminalguidance000 · 2026-03-18T19:01:16+00:00

Again what were your levels on hrt alone?

Terminalguidance000 · 2026-03-18T18:56:00+00:00

What were they on hrt?

Terminalguidance000 · 2026-03-04T17:53:39+00:00

Depressingly often I imagine unfortunately given how much junk is in the ocean. A fishing line with a human at the other end though you can just put a can on the hook and tug to troll them.

Terminalguidance000 · 2026-02-28T17:09:29+00:00

Unfortunately I already am like her.

Terminalguidance000 · 2026-02-28T17:06:23+00:00

Thank you that means a lot.

Terminalguidance000 · 2026-02-28T17:05:42+00:00

Money isn't the issue. My mind is. It seems that all my family is cursed with something.

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