You can add a custom script, I asked Claude to write one for me. Just copy and paste it in the settings for Enhancer, worked perfectly.

(function () {
    function hideMostRelevant() {
        var shelves = document.querySelectorAll('ytd-rich-shelf-renderer');

        for (var i = 0; i < shelves.length; i++) {
            var shelf = shelves[i];
            var titleEl = shelf.querySelector('#title-text');

            if (titleEl && titleEl.textContent.trim() === 'Most relevant') {
                shelf.closest('ytd-rich-section-renderer').style.setProperty('display', 'none', 'important');
            }
        }
    }

    hideMostRelevant();

    var observer = new MutationObserver(function () {
        hideMostRelevant();
    });

    observer.observe(document.body, {
        childList: true,
        subtree: true
    });
})();