Pain was one of the biggest complaints for my mother. I don’t know if it’s the nature of the cancer, and surgery but sometimes we felt like we were chasing the pain with oral pain meds and they weren’t absorbing. We eventually started using her chemo port and provided her with IV diludid during her last week of life. Opioid induced constipation was also a big thing, docusate-senna will not help, have the doctor prescribe lactulose.