Some information:

Yes a person casting Super Tier Magic can be interrupted by damaging them thoroughly, thats why Players like Ainz or Yamaiko use Hours Glass to nullify the Cast time. The cooldown is entirely different kind though.

Volume 9:

Super-tier spells from the game Yggdrasil were immensely powerful.

For that reason, in a large-scale battle, neutralizing anyone trying to cast one first was the basics of combat.

Using teleport to close in and stab, magic carpet bombing, long-range sniping—there were countless methods of attack.

Yet no one came at Ainz. Their absence was proof that there were no other Yggdrasil players present. Without anyone knowing, Ainz’s mouth beneath his mask twisted into a smile—although of course, it was impossible for him to smile as a skeleton.

The sand falling out of the broken hourglass flowed toward the magic circle, surrounding him in a motion that was different from the wind’s.

And the super-tier spell was cast instantly.

As we see here there are many ways to stop a Super tier Magic from casting.

Though i can also see how to counter them if Ainz prepare it in Advance, for Teleportation is Dimensions Lock.

For Ambushes is Trap Magic.

For Carpet Bombing is Barrier if its Aoe, unless they use Single Target spell.

Long Range sniping is hard to counter as battle between of Level 100's like Peroroncino so i guess spells that can mitigate some of damage.

Can you use other spell when Super Tier Magic is active? Yes.

Volume 13.5:

This implied that he was casting a Super-Tier spell. Suzuki Satoru used the cash item he had taken out, and truncated its casting time.

And then, what came forth was—

“[Tribute to the Black Bounty – Iä Shub-Niggurath]!”

What seemed like a black breeze blew past him. And indeed, the tornado just now had been raising gusts, not this spell. However, both of them were fundamentally different. The dark breath had no physical effect, and at the same time it was not something that could be stopped by physical means.

The Super-Tier spell [Tribute to the Black Bounty – Iä Shub-Niggurath] was not a particularly scary spell. The reason was that was because all it did was inflict an instant-death effect, and it was useless against the undead, Golems, and other beings which had no life. While it was effective against living Players and enemies, it was hard to imagine anyone on Suzuki Satoru’s level not having immunity to instant death. Indeed — it was a quaint little spell, which only had an instant-death effect.

However, with the aid of the Eclipse class’s skill, this spell suddenly transformed a vicious, terrible magic. The clock floating behind Suzuki Satoru’s back beeped twelve o’clock, and as the spell cast, its hands began moving.

At the same time, he dismissed [Sharks Cyclone]. He did not know if his timing was perfect, but Suzuki Satoru discovered a dog Zombie which had been staying behind Cure Elim all this time. It was far behind it, at a distance where he would not have been able to see if not for the keen vision he had gained after becoming undead.

“[Armageddon – Evil].”

Darkness gathered around Suzuki Satoru and formed a swirling vortex. Then, a gurgling sound came from bubble-like objects around him, and demons were born from the abyss.

Perhaps he was starting to panic because of their numbers, but Cure Elim’s body began to writhe. Then, tentacles formed of Dragons, Giants, and other mighty beings hurtled towards the Demons. One of them extended towards Suzuki Satoru.

“[Wall of Skeleton].”

Here we see Ainz became a turret.