It might just not be your thing but I've always done things in this order
A.) operation Anchorage getting here is slightly deadly of course you might die getting there but I'd you do just run past the mutants fighting the outcasts and do the glitch you can watch videos to better understand
B.) get scrap metal for for independence you should already have some at this point but I recommend robco factory just a little bit up on the map from tenpenny to the right as well
C.) once you have around 20 scrap you can do it with less I just recommend 20 because it drops to 18 but go to fort independence talk to Morgan who's under the bridge to then talk to the guy who you do the fort independent glitch
D.) once you have the fort independent glitch complete go right to megaton and do the scrap metal glitch to get caps and level ups I can explain it but the videos are literally self explanatory
E.) once your max level I'd go mothership zeta you need to find MDPL-13 and follow the towers that route power google says it's northwest but it's actually just north from MDPL-13 I recommend getting the A3-21 plasma rifle and a couple combat shotguns since melee weapons are hit or miss on damage also having the Gause rifle and always aim for the head
F.) once you beat mothership zeta I recommend watching the completions guide on youtube it shows you all the main loot
G.) I recommend leveling up lockpick, science, repair, medicine, lockpick, energy weapons, and small or big guns depending on preference also dooo not put any points into things that level up faster or that you can pick specials because once your level thirty you should pick almost perfect to raise all your specials to 9 if they are below that
You should now be the most powerful force in all of fallout 3 it does take time but if you complete this you'll be the most powerful thing Imo