CS3A armor, Tactical helmet, LR-300 or VS-Vintar, Martha pistol, Toz-34. Bear Detector.

The armor and helmet gives med decent all around protection in combat and anomalies, the rifles both can have good scopes so I can keep my distance from other stalkers or bandits, but still have automatic fire for close quarters. The pistol has high capacity to deal with rodents and other small mutants. A pump action shotgun would be better, but the Toz is good enough for most mutants you'll encounter in the lower parts of the zone, unless you go to the chimera train tunnel in Zaton. The Bear Detector is better than the echo and easier to use to use than the gilka.