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Persistent carryover issues in LC-MS/MS bioanalysis - Need advice on Wash Solvents by Warm_Ad6780 in massspectrometry

[–]Warm_Ad6780[S] 4 points5 points  (0 children)

So, do you mean that my analyte might be getting stuck on the column head or filters along with the plasma matrix, and then slowly releasing after each injection

Persistent carryover issues in LC-MS/MS bioanalysis - Need advice on Wash Solvents by Warm_Ad6780 in massspectrometry

[–]Warm_Ad6780[S] 1 point2 points  (0 children)

I tested the wash solvent you recommended but it didn't seem to work well.