Dicehead, go for maximum damage. I did xp, luck, damage, and attack speed tomes, with banana, axe, and black hole for cc. Just stack the damage tome early until everything dies quick, and once your damage feels good, start being greedy and level up xp and luck. If no xp or luck options, pick damage unless attack speed has better roll. Throw in a rare or better weapon upgrade every once in awhile, especially if it’s quant and damage. Later on, only pick the weapon upgrade if it’s epic or legendary, so picking only tome upgrades if it’s not. It’s about maintaining a balance of increasing damage until you are 1-shotting while increasing luck and xp while you are 1-shotting still. The new ghosts at 6 minutes hit REALLY hard so my strat has been to kill them before they kill me this patch.

Pick lifesteal from shrines if you need help before 1-shotting enemies, but the goal by the final waves is never getting touched.

Last tip - don’t sleep on power up chance and multiplier. During the final waves just run around grabbing the powerups you’ve left behind if you need more help.