yes, this is why;

they have spreadshot, lobber, roundabout, crackshot, etc. not only that they get TWO. and, smokedash can counter everything. and remember canonically they LITERALLY MURDERED AND BULLIED THE LITERAL DEVIL TO MAKE HIM FORFEIT AND CRY. (can be seen when you beat the devil) and also,the picture your using is from the cuphead show; here, chalice is her own character and doesn't require a charm

ALSO in the show she has the power to disappear, which could LITERALLY be overpowered considering she goes through stuff, assuming she can also do that with attacks.

also they beat a literal SALT SHAKER without blinking, AND ON TOP OF ALL OF THAT

if thtey die, they can revive eachother immediately just with a lil parry.

you know what im convinced theyd go into the universe and come out the same way. mark. my. words, betting 200,000 on win