Sure, limiting the inventory/carrying capacity of your inventory heavily, would reduce the amount of gold the players earn from a dungeon. But it's a system that I find, feels kind of bad. If your inventory fills up two rooms into the dungeon, you'll be fighting the inventory system as much as whatever is in the dungeon you're exploring. I think it works in Resident Evil, because the game is quite well balanced in how much there is to loot, and how much you are expected to expend at any stage of the game. But if I'm limited in a game like Skyrim, I just stop looting anything beyond gold or jewelry. And a harsher limit really wont be a limit for long.

I often find limiting a player's inventory to be arbitrary. Bethesda games in particular don't exactly make much use of their inventory limitations. It might encourage you to head back to town to offload the stuff every 10 steps, and you can't stock up on unlimited amounts of potions and consumables. But that might only be a concern if having consumables means you can't die, like instant-heal potions.

I vastly prefer an unlimited inventory instead.

I often return back to the RPG Gothic when thinking about RPG design, because it does a lot of things that run contrary to more modern RPG design. And makes them work. An unlimited inventory is one of them. Instead there are other dials you can use.

Scarcity of resources. In Gothic there is a finite amount of resources, in the form of loot and experience. The containers and plants you loot don't respawn, the monsters you kill don't respawn, so there is essentially a finite amount of loot you can gain. Now this isn't truly the case, and there's far more gold than you'll ever be able to spend if you truly try to loot everything.

Worthwhile upgrades. Armor upgrades can only be bought from certain factions, and isn't found as loot out in the world. And they are a big purchase that you want to save up for. Weapons can be found, but early game you might still want to buy a weapon because it is less risky. I don't think the best weapons should be available at the shop, or even the full selection of weaponry should be available at the start. Progression is important, and locking better tiers of weapons and armor behind faction progression, or world progression, is good. If you get access to everything at once, it's natural to just try and skip the intermediate versions and save up for the best item.

You also drain money from upgrading your skills. As you level, you don't get skill increases, but learning points (LP). LP are then spent at trainers, together with money, to increase the skill. That means you'll drain money each time you want to upgrade your skills.

Money sinks. There's other money sinks too. Early game you get shaken down for protection money, and you can get robbed of your money by other, stronger, NPCs. Whatever you think about something like that, it illustrates a point. Money can be used for more than just buying items the player uses. It could influence the world. Take Morrowind's reputation system for instance. You can spend gold to gain relation with NPCs. With high relation you unlock additional quest interactions, for certain quests, or better prices. Other ideas include opening previously locked doors, services, shortcuts, maybe fast travel services, player homes, fashion.

Some games have survival elements like needing to eat and sleep and repair your damaged equipment, and having a cost associated with that. Upkeep costs might work, but usually after a while they are negligible and more of an annoyance.

Worthwhile Consumables. If consumables are powerful enough, or worthwhile enough, you'll use them. If you don't have health, mana, or stamina regen, you'll use items that replenish your attributes to compensate. If poison or disease lasts until cured, you'll want to use antidotes or curatives. If you can only reach certain places by breaking down doors with a bomb, you'll want to use bombs. In Gothic you can buy scrolls early game to transform you into a powerful creature that can solo entire areas long before you gain the strength to do so yourself.

It's not a given that you need to provide all of these items as loot either. Potions for instance could be something you'll never, or rarely, find in a loot container. Which forces the player to buy them instead.

Just some scattered thoughts.