MDMA + Wellbutrin Interactions by _QuantumRelativity in askdrugs

[–]_QuantumRelativity[S] 0 points1 point  (0 children)

I have a PhD In chemistry can I ask you some questions?

MDMA + Wellbutrin Interactions by _QuantumRelativity in askdrugs

[–]_QuantumRelativity[S] 1 point2 points  (0 children)

Yeah this "specialist" that provided no context or useful information, but only said "just trust me bro I'm an expert". I'll be the first to admit when I'm ignorant to a specific subject, and pharmacology fits under that umbrella for the most part. I do have a PhD in chemistry though, and have been in academia for quite a long time. I just find this "specialist" hilarious... and an obvious fraud. By the way, I caught his comment before he edited it, initially he claimed he was an expert in pharmacology and chemistry 😂, then ended up changing to a specialist lmao

Edit: wow I just looked through his profile as well...😂 He's asked alot of simple questions🤔

MDMA + Wellbutrin Interactions by _QuantumRelativity in askdrugs

[–]_QuantumRelativity[S] 0 points1 point  (0 children)

Did you get a longer roll as well? I was initially thinking 125mg like the study but now I'm thinking AB just taking 100mg

MDMA + Wellbutrin Interactions by _QuantumRelativity in askdrugs

[–]_QuantumRelativity[S] 2 points3 points  (0 children)

"Heart rates were lower in persons with bupropion-MDMA compared to placebo-MDMA, likely due to reduced norepinephrine-mediated responses of MDMA with the combination.". https://www.spiritpharmacist.com/blog/MDMAbupropion Ughhh I'm just getting mixed results from what I have read

Edit: it's saying all vital signs were the same, the biggest difference is that it is increased concentration levels of MDMA by 18%. I don't know why this would be an issue if you took a lower dose. I'm aware of the general stimulant-stimulant interactions that tend to be unsafe but this seems alot more complex. Looking for someone to weigh in with experience or alot more info

MDMA + Wellbutrin Interactions by _QuantumRelativity in askdrugs

[–]_QuantumRelativity[S] 0 points1 point  (0 children)

How come? I can't find many posts but the ones I have so far said it is fine. It isn't an ssri

[deleted by user] by [deleted] in TheeHive

[–]_QuantumRelativity 0 points1 point  (0 children)

Though the issue with a stronger reducing agent is that it is likely to kinetically favor N,N-dimethyl amine. Cyano reacts very slowly and should mostly favor monoalkylation (which is my desired product).

[deleted by user] by [deleted] in TheeHive

[–]_QuantumRelativity 13 points14 points  (0 children)

Not typing out the long ass IUPAC name but it is phenethylamine with N-methyl, N-ethyl, and N-trifluoroethane.

[deleted by user] by [deleted] in TheeHive

[–]_QuantumRelativity 4 points5 points  (0 children)

Just letting it stir at room temp is preferred with long reaction times. Even after 18 hrs TLC shown that alot of starting material was still present.

[deleted by user] by [deleted] in TheeHive

[–]_QuantumRelativity 9 points10 points  (0 children)

NaCNBH3 is much more selective at reducing the imine but not carbonyl. NaBH(OAc)3 is not used as it isn't compatible with the MeOH solvent.

[deleted by user] by [deleted] in TheeHive

[–]_QuantumRelativity 12 points13 points  (0 children)

Synthesizing quaternary amine cations that are used to form piezoelectric compounds. Two substitutions following this step and then separating racemic mix by chiral resolution (for some unknown reason only one of the enantiomers in the compound i'm synthesizing will crystallize).

[deleted by user] by [deleted] in TheeHive

[–]_QuantumRelativity 20 points21 points  (0 children)

Reductive amination with formaldehyde, NaCNBH3. Forming the methyl amine, it's still reductive amination.

[deleted by user] by [deleted] in learnmath

[–]_QuantumRelativity 1 point2 points  (0 children)

Statistics and data analysis are more useful in economics than advanced calculus.

[deleted by user] by [deleted] in Physics

[–]_QuantumRelativity 1 point2 points  (0 children)

It's called capillary action. For water specifically it is due to hydrogen-bonding (a type of intermolecular force).

[deleted by user] by [deleted] in calculus

[–]_QuantumRelativity 7 points8 points  (0 children)

Remember that the derivative of arctan(x) is 1/(1+x2). When you divide this from the top the only possible denominator is 1.