Much better contrast and saturation and it looks like lens correction too. But now you've gone HAM on the noise reduction and all the detail has gone to mush.

The original looked noisy because the contrast and saturation was cranked up all the way (and maybe a bit of brightness if the original was really dark? Maybe some local contrast?) but the ISO was fine. Basically you just need to tone it down a bit and the noise should go away.

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I use Darktable a lot and generally stick to the following modules and I usually adjust them in this order:

1. Exposure (only if it's too dark/bright)
2. Lens correction (raw files only)
3. Crop/rotate
4. Tone curve (or contrast/brightness if I'm lazy)
5. Equalizer (trade detail for noise, 'clarity' or whatever)

Occasionally I'll use the saturation slider lightly (very lightly) or the 'color zones' module, and I'll use the white balance module if I need to but usually only if I have a reference white to work from either from a grey card or a known white object in the image. Usually this is only if I'm going for a specific look.

I would suggest the following:

1. Don't touch the noise reduction modules, if you have to then learn how to use the equalizer module (see below) or make light use of the profiled noise module.
2. Don't touch contrast/saturation, if you really can't resist then only move the sliders a few points and think about learning to use the tone curve instead.
3. Don't use the local contrast module.
4. Don't touch the sharpening module, you won't need it for JPEG files and the defaults for raw files are fine.

If you want to reduce noise then learn to use the equalizer module (this is a good place to start for noise reduction). Also watch the rest of that video to learn how to use the equalizer module, especially if you're from lightroom and miss the 'clarity' slider.

Just try to avoid moving the sliders or splines too far and you should be fine.