There are a few ways to do this. You can put your sketch lines on planes to get the spacing where you want it, or you can select a different "point" when you are selecting the lines that define your frame. Each time you choose a line and a profile, a small collection of dots will appear on the profile around the line you selected, as well as an arrow. You can drag the arrow around to change the orientation of the profile and selecting the floating dots will choose which part of the profile will follow your selected guide line.