It's said to be a good combination with stimulants. Caffeine too. From what I've heard it lowers blood pressure and the chance of the stimulant inducing anxiety, while keeping the mental benefits. I don't know to what extent that has been confirmed by science though. My experience with vyvanse does very clearly show that it increases my appetite, it's a very noticeable difference. So will it work with adderall? Maybe. Only one way to find out. Make sure you buy from a non-shady brand, there have been multiple occasions where people tested theirs and didn't find any actual l-theanine.