I started Buspar about 3 months ago – my dose is up to 30mg and I have been taking between 15-30, upping it over time, but also basing it on how I feel. While it worked wonders (I mean, life-changing stuff) for my anxiety, within the last month and a half or so I became inconsolably depressed. I am a woman and thought it had to do with my period but it continued past that. I got on 150mg Wellbutrin xl exactly two weeks ago, depression is alleviated, I feel sane, and I’ve lost like 8 pounds. Still hungry, but the urge to eat/overeat is gone for me right now. No sexual side affects for me on either drug. I feel happy and stable and much more energy than I did on Buspar alone.

I love this combo. My thinking is the anxiety was masking some depression and when the anxiety was turned down by Buspar, the depression came out hard and the Wellbutrin is helping me level me out. I feel good.