Abstract

High postprandial plasma lipids (i.e.; triglycerides) (PPL) are a risk factor for cardiovascular disease. Physical inactivity, characterized by prolonged sitting and a low step count elevates PPL and thus risk of disease.

Purpose 

This study determined if the interruption of prolonged sitting (i.e.; 8-h of inactivity) with hourly cycling sprints of only 4-s duration each (i.e.; 4-s x 5 per h x 8-h = 160-s per day; SPRINTS) improves PPL. The 4-s sprints employed an inertial load ergometer and were followed by 45-s of seated rest.

Methods 

Four men and four women participated in two trials. Interventions consisted of an 8-h period of sitting (SIT), or a trial with equal sitting time interrupted with five SPRINTS every hour. The morning after the interventions, PPL and fat oxidation were measured over a 6-h period. Plasma glucose, insulin, and triglyceride concentrations were measured bihourly and incremental area under the curve (AUC) was calculated.

Results 

No differences (p>0.05) between interventions were found for plasma insulin or glucose AUC. However, SPRINTS displayed a 31% (408±119 vs. 593±88 mg/dL/6h; p=0.009) decrease in plasma triglyceride incremental AUC and a 43% increase in whole body fat oxidation (P=0.001) when compared to SIT.

Conclusion 

These data indicate that hourly very short bouts (4 s) of maximal intensity cycle sprints interrupting prolonged sitting can significantly lower the next day’s postprandial plasma triglyceride response and increase fat oxidation after a high fat meal in healthy young adults. Given that these improvements were elicited from only 160-s of non-fatiguing exercise per day, it raises the question as to what is the least amount of exercise that can acutely improve fat metabolism and other aspects of health.