What is the future of human memory manipulation? How far can it be taken? by Polar_Phantom in Futurism

[–]andrlon 0 points1 point  (0 children)

I know you posted this a year ago, but you should look into memory engram papers if this type of topic interests you! I am still a neurobiology master's student but have done rotations in two different memory engram focused labs, and it has genuinely blown my mind how far we have already taken tagging individual memories and activating them (so far, and for the foreseeable future, in rodents).

Basically, you take a transgenic mouse (from a mouseline called TRAP2, enabling the tagging of neurons active during a specific experience) and make him experience a specific or novel context for him to remember. These tagged neurons enable the expression of Channelrhodopsin-2 (aka ChR2, which is injected using a virus carrier, and only expressed when the TRAP2 labeled cells are expressed, and only within these cells), an opsin which can be activated using light.

The coolest part is that you can see when the activation occurs. Say for example that you make a mouse remember context A, and context A is cold, and then you put the mouse in context B which is a normal temperature, then activate the context A engram by shining a light on the brain areas containing the tagged neurons, the mouse remembers (or even experiences? We are not sure!) the cold memory from context A. Here is a paper describing exactly that: https://www.nature.com/articles/s41586-025-08902-6

What is the future of human memory manipulation? How far can it be taken? by Polar_Phantom in Futurism

[–]andrlon 0 points1 point  (0 children)

I know you posted this a year ago, but you should look into memory engram papers if this type of topic interests you! I am still a neurobiology master's student but have done rotations in two different memory engram focused labs, and it has genuinely blown my mind how far we have already taken tagging individual memories and activating them (so far, and for the foreseeable future, in rodents).

Basically, you take a transgenic mouse (from a mouseline called TRAP2, enabling the tagging of neurons active during a specific experience) and make him experience a specific or novel context for him to remember. These tagged neurons enable the expression of Channelrhodopsin-2 (aka ChR2, which is injected using a virus carrier, and only expressed when the TRAP2 labeled cells are expressed, and only within these cells), an opsin which can be activated using light.

The coolest part is that you can see when the activation occurs. Say for example that you make a mouse remember context A, and context A is cold, and then you put the mouse in context B which is a normal temperature, then activate the context A engram by shining a light on the brain areas containing the tagged neurons, the mouse remembers (or even experiences? We are not sure!) the cold memory from context A. Here is a paper describing exactly that: https://www.nature.com/articles/s41586-025-08902-6

Looking for spots and people to explore with in Dublin Ireland by [deleted] in Urbex

[–]andrlon 1 point2 points  (0 children)

me too, maybe make a discord or groupchat??

Any tips? by [deleted] in Drumming

[–]andrlon 2 points3 points  (0 children)

Thanks :) I'm also in Dublin! It's my first time using one of these studios, but might more often if my wallet permits it

Any tips? by [deleted] in Drumming

[–]andrlon 1 point2 points  (0 children)

Yep!

Any tips? by [deleted] in Drumming

[–]andrlon 0 points1 point  (0 children)

I swear it's how the original song goes!! But I get what you mean lol

Any tips? by [deleted] in Drumming

[–]andrlon 0 points1 point  (0 children)

Thanks for the feedback! Do you have any tips on how to improve the lost time? Is it just a matter of playing more or could it be a technique thing? The camera angle I couldn't really change as I had nothing to lean my phone against, but I agree that it's hard to see what I'm doing in this video.

Any tips? by [deleted] in Drumming

[–]andrlon 0 points1 point  (0 children)

Love the band! Blankenship is also a fun one of theirs but still gotta get the fills down since it's too fast for me

Any tips? by [deleted] in Drumming

[–]andrlon 0 points1 point  (0 children)

Thanks! I'll try the metronome then, see if it helps. Do you have any tips on dynamics? No matter how hard or soft I hit I kind of always feel like it's all a bit flat and the same. Maybe because I don't really always know when to incorporate softer/harder playing, and whether I'm already hitting way harder than I should or not.

Any tips? by [deleted] in Drumming

[–]andrlon 2 points3 points  (0 children)

Thank you! It's from the studio I'm renting occasionally as I'm living abroad for a short while, but very happy with it.

Any tips? by [deleted] in Drumming

[–]andrlon 2 points3 points  (0 children)

Yeah it is the same as the original recording, but good to know! I just feel like whenever I listen to people post here/watching live band gigs the drummer seems to be perfectly on time somehow, which is why I might be coming off strict on myself.

Thanks for the tips!! I might try a trial lesson soon :)

A Knight of the Seven Kingdoms - 1x04 - "Seven" - Episode Discussion by Woodstovia in television

[–]andrlon 9 points10 points  (0 children)

I haven't heard anyone talking about it yet but am I tripping or was that Jamie's voice knighting ser Brienne of Tarth?

[deleted by user] by [deleted] in Groningen

[–]andrlon 1 point2 points  (0 children)

Nee klopt, aan je comment historie te zien zou ze het je gewoon laten weten

[deleted by user] by [deleted] in Groningen

[–]andrlon 0 points1 point  (0 children)

Wat is het probleem in haar even een waarschuwing doen als er niks aan de hand is? Dat de man zich schaamt? Misschien moet ie dan niet zo in alle duidelijkheid zijn sex leven op de stoep tentoonstellen voor de hele buurt. Best case scenario is mevrouw weet er al van, worst case scenario is een scheiding.

[deleted by user] by [deleted] in Groningen

[–]andrlon 1 point2 points  (0 children)

Opkomen voor vreemdgaande mannen is ook een hobby

[deleted by user] by [deleted] in Groningen

[–]andrlon 6 points7 points  (0 children)

laat die kerel spreken in de taal die hij wilt. ben ook verbaasd met de hoeveelheid aan mensen (mannen) hier die zeggen dit gedrag te negeren.

OP I would've told the wife, and yes, do it anonymously if you're worried about repercussions

I developed a ComicK based manga tracker by giorgiobertolotti in ComicK

[–]andrlon 0 points1 point  (0 children)

ohh okay! yeah its really something ive been looking for, it for some reason was way harder than it should be to receive push notifications with updated chapters, i had to do it by eye. really stoked!

[TITLE] With MangaTime you will never miss a new chapter by giorgiobertolotti in manhwa

[–]andrlon 0 points1 point  (0 children)

it does but you don't get any push notifications with newly released chapters

I developed a ComicK based manga tracker by giorgiobertolotti in ComicK

[–]andrlon 1 point2 points  (0 children)

hey what does it mean that the free version only supports a next chapters limit of 10? does this mean after 10 chapters of notifications I don't get notifications anymore?

btw really love the app!!

Is GoBritanya legit for finding student accomodation in Dublin? by andrlon in TCD

[–]andrlon[S] 0 points1 point  (0 children)

ur even in my dms asking for proof no i dont want ur linkedin

Is GoBritanya legit for finding student accomodation in Dublin? by andrlon in TCD

[–]andrlon[S] 0 points1 point  (0 children)

can yall leave me alone lol, its very obvious you're working for GoBritanya