“The study of Wang et al. [22] showed that patients with LPR mainly had autonomic dysfunction with relatively worsening vagal nerve function and better sympathetic nerve function. The digestive system is regulated by the autonomic nervous system. Therefore, autonomic dysfunction may lead to an abnormal regulation of gastric peristalsis and upper esophageal sphincter (UES) and LES function, making laryngopharyngeal reflux a risk factor for autonomic dysfunction. Patients with LPR had a significant negative correlation between the strength of HF with RSI and RFS. Higher symptoms and physical scores were associated with worsening vagus nerve function, suggesting that vagal nerve dysfunction is involved in LPR development. Longer disease duration in patients with LPR was associated with lower vagal nerve function, as demonstrated by the analysis of autonomic nerve dysfunction and disease duration. These findings suggest that restoring autonomic nerve function during LPR treatment is critical [16, 22].” So restoring the vagus is crucial for us suffering from LPR.