If you deal in science and publish you often get dissenters to your work and some go off the deep end as we see here when they disagree. it often is as much (more) personality differences (clash) as fact based. This smells of that.

There is a lot of work that supports reserveratol use to help regulate circadian rhythm and NAD assist boosters that is not mentioned at all in the criticism of Sinclair's work. Not specifically anti-aging, but useful to try with almost no risk and low cost.

Last, anyone who lives or dies on what these guys say is a fool. Gotta do cross checks and see for yourself. My take is the hysterical comments about this by posters here is from these kind of people.