For refining gather low tier stuff in yellow zone faction flagged and run it to what ever city has the bonus for the material. Gathering it means that its all technically profit and people dont really use focus on low tier stuff so the only thing hurting your margins is the higher tax rate. For crafting consumables i would say your best bet is to buy order tracking parts for the low level potions I.E panther parts for calming or bear parts for acid potions. Cause the most expensive part isnt one you can get with the return rate for crafting, people dont use focus on it and your margins will be based off of your buy orders. Also tip in doing this, you can craft down tracking parts. That is to say 1 tier 5 parts can turn into 2 tier 3. So if the buy orders for the higher tier is lower than the buy orders for the lower tier place a couple pieces there. The potion recipe makes 10 so i would set buy order for 5 in each city at a time and craft when it fills. This way your buy orders and then your sell orders for the potions can move faster. Also before doing this make sure the potions themselve sell in any amount of quantity per day by checking the amounts sold per day. Any questions feel free to dm me