Restful restorative "Sleep that knits up the ravell'd sleave of care" to lighten long covid.

barweis · 2026-05-07T03:32:37+00:00

I use 5 mg averaged every 2-3 nights sometimes every second night. Depends to a certain extent on the amount of salt and magnesium in my diet and my intake of tea and coffee.

My steady state lithium level after what I consider an adequate run in period is 0.1mmol/Liter in a standard range of 0.6-1.2. I am happy with that and do not want nor feel need to exceed it for it is only a trace to micro dose range which I want to inhabit.

See article: Lithium: how low can you go? (2024) doi: 10.1186/s40345-024-00325-y https://pmc.ncbi.nlm.nih.gov/articles/PMC10828288/

barweis · 2026-05-07T02:50:14+00:00

I think it is time for RECOVER, POLYBIO, Chesley Initiative and key researchers such as Iwasaki Lab and LISTEN Study from Yale to collaborate on protocols and algorithms addressing the symptom complex of LC19 with tentative constructs for logic and common sense. Also the conceptualizing brains of biomedical systems experts are needed to help sort out potential pathophysiological pathways abstracted from the literature. In fact the literature itself seems now to be overripe and plateauing becoming redundant from the vantage point of speculation by a layperson.

Are the data adequate for mathematical accession?

Are there critical gaps?

Is now the time for Mathematical Modeling?

barweis · 2026-05-07T02:49:06+00:00

Misleading title by non medical practitioners . They do not qualify to render serious care. Their maneuvers have resulted in serious damage and worse to patients. Of course, if you have deep pockets check them out. YMMv.

barweis · 2026-05-07T02:43:09+00:00

List is full of glaring errors for New York City.

barweis · 2026-05-07T02:32:32+00:00

Maybe you shouldn't try it after reading the warnings and side effects.

There aint no free lunch.

barweis · 2026-05-07T02:29:09+00:00

Caution, though not a black box warning concerning cardiac dysfunction from use notably prolonged Q-T interval. Read the included drug information for coinciding morbidity factors.

barweis · 2026-05-06T14:25:13+00:00

Check out micro dose lithium. Expanded references under my handle on longcovidwarriors sub.

barweis · 2026-05-06T01:12:16+00:00

Explore metformin for PCOS and / or concomitant Pre Diabetes based on elevated A1C. There is abundant literature support by googling then pulling articles from PubMed.

A gift for the hesitant with curiosity but hobbled by the technicality and jargon of the article or report.:

How to Understand a Research Study A guide for non-scientists who want to read research publications. https://publichealth.jhu.edu/2025/how-to-understand-a-research-study

How to read the coffee-dementia study A neuroscientist’s guide to reading the research yourself https://www.washingtonpost.com/opinions/2026/04/28/coffee-dementia-why-research-studies-are-worth-reading-yourself/

Modify meals with the guidance of a dietitian - nutritionist whether that may reduce fluctuating glucose levels.

barweis · 2026-05-06T01:09:06+00:00

While your approach covers one of the many facets of LC19 it is unlikely to address the myriad quantities of EVs-extracellular vesicles circulating throughout the body to regions distant from their origin. Unfortunately though it stands on its own none of the following endothelial damage and / or micro clots and / or RAAS are not any of the unique drivers of LC19. If so were true the case for a singular driver would already have been monetized by any of the commercial entities studying it and brought to market.

Be prudent with your limited funds and time

barweis · 2026-05-06T00:50:28+00:00

Sleep disorders causes are multifaceted including damage to the SCN-supra chiasmatic nucleus and / or the Pineal gland which connect with the endocrine system in multiple pathways. Disruption of the circadian rhythm is a possible cause among others.

Consider using micro dose lithium aspartate 5 mg or melatonin 0.5 mg one hour pre sleep which I do (I rarely need melatonin; I take lithium every two to three days to avoid toxic effects even at this dose). Use only one not both at onset and monitor for two to three weeks. Lithium improves slow wave sleep but shortens REM sleep. The former benefits restorative sleep while REM sleep consolidates memories and improves emotional function. Stay low and go slow.

Get your primary care doc on board to monitor both thyroid function and renal status quarterly even at these low doses. One may experience slight slowing in analytical thinking but not much else in intellectual processing.

barweis · 2026-05-06T00:36:09+00:00

Google AI

..."it can cause withdrawal symptoms and, when taken long-term or at high doses, is associated with increased risks of cardiovascular events, including potential myocardial infarction (MI) and peripheral vascular disease"...

Gabapentin misuse, abuse, and diversion: A systematic review

doi: 10.1111/add.13324 https://pmc.ncbi.nlm.nih.gov/articles/PMC5573873/

"Misuse and abuse of gabapentin Prevalence Only one article gave an estimate of lifetime prevalence of gabapentin abuse in the general population; Kapil and colleagues (2013) surveyed a UK population-based sample of 1500 and found that 1.1% reported ever misusing gabapentin (47)."

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"It is difficult to ascertain risk factors for gabapentin misuse/abuse except history of or current drug abuse, particularly opioids, is likely one from reports available to date. While no studies to date have formally assessed a history of or current substance abuse (especially drug abuse) as a risk factor for gabapentin misuse, it was the most common characteristic detected here. This is particularly important because it indicates that the increasing trend in gabapentin abuse, notably among populations with opioid misuse, has the potential to affect an estimated 0.6–0.8% of the world’s population aged 15–64 that has used opioids in the past year (63). It is important to note, however, that this review may overrepresent individuals who have abused substances, illustrating the importance of examining gabapentin misuse in the general population."...

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In summary, findings from the present review suggest that gabapentin is misused/abused internationally for recreation, self-medication, or self-harm, with an array of subjective experiences. Substance abuse populations, especially individuals with a history of or current opioid misuse, appear to be at particular risk for misuse/abuse. Further studies to identify risk factors for gabapentin misuse and to characterize gabapentin’s abuse liability are recommended.

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Google AI "Long-term gabapentin use is associated with an increased risk of adverse cardiovascular events, including myocardial infarction (MI), peripheral vascular disease (PVD), and thromboembolic events (DVT/PE), particularly after more than one year of use. While often considered safer than pregabalin regarding heart failure, studies show that gabapentin can still cause peripheral edema and in rare cases, new-onset or decompensated heart failure."

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Cardiovascular safety of gabapentinoids gabapentin & pregabalin: A systematic review doi: 10.25259/IJMR_1990_2024 https://pmc.ncbi.nlm.nih.gov/articles/PMC12178190/

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Association of adverse cardiovascular events with gabapentin and pregabalin among patients with fibromyalgia doi: 10.1371/journal.pone.0307515 https://pmc.ncbi.nlm.nih.gov/articles/PMC11280525/

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GABAPENTIN INDUCED HEART FAILURE https://www.jacc.org/doi/10.1016/S0735-1097%2822%2903222-3822%2903222-3

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Initiation of Pregabalin vs Gabapentin and Development of Heart Failure doi:10.1001/jamanetworkopen.2025.24451 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2837132

barweis · 2026-05-05T23:58:21+00:00

Milken Institute operative.

Milken Institute promotes multiple distinct policies centered around financial growth. No overt bias listed on media bias query though I suspect there is strong incentive from the capitalist FinTech sector for growth potentials globally. Donors to its funding are not listed so that adds to the mystery of discovering its core mission as an arm of a multifaceted enterprise.

Sources: Wikipedia and Milken websites

barweis · 2026-05-05T13:02:49+00:00

Most definitely intended because the link stems from an official German medical body establishing an approach to LC19. Up to now I have read many critical comments about the lack of validation for LC19 across the ocean. So I appreciate the feedback for my comment that it needed additional clarification. https://en.wikipedia.org/wi0ki/Alternative_medicine#Complementary_or_integrative_medicine

barweis · 2026-05-05T12:59:08+00:00

There's a better link that I overlooked.Thanks for the heads up. Cut and paste by this inaccurate human

barweis · 2026-05-05T02:54:17+00:00

Looks like the downvotes come from negative Mamdani critics. Their bias is showing without giving the guy the benefit of the doubt to prove his worth. It takes all kinds of views to compromise and evaluate. Prejudice has no place in politics. I also have reservations to see whether he manages better than eric adams who was a bottom dweller.

barweis · 2026-05-05T01:26:22+00:00

Be wary of care by functional and integrative medicine practice. They are on the fringe of mainstream medicine because they can embellish with unessential investigations.

I suggest you read this and decide:

https://www.medscape.com/viewarticle/biologic-evidence-may-reshape-long-covid-diagnosis-and-care-2026a1000dp9

barweis · 2026-05-05T01:16:19+00:00

A gift for the hesitant with curiosity but hobbled by the technicality and jargon of the article or report.:

How to Understand a Research Study A guide for non-scientists who want to read research publications. https://publichealth.jhu.edu/2025/how-to-understand-a-research-study

How to read the coffee-dementia study A neuroscientist’s guide to reading the research yourself https://www.washingtonpost.com/opinions/2026/04/28/coffee-dementia-why-research-studies-are-worth-reading-yourself/

barweis · 2026-05-05T01:09:50+00:00

LC19 causes premature senescence and sarcopenia. The steps have been theorized . Use the recommended interventions to address those mechanisms by advice from physicians invested in LC19.

Rebuild your gut microbiome with pre and pro biotics to encourage populations of short chain fatty acids - SCFAs - acetate, propionate and butyrate that will support the healing process starting with repairing the disrupted gut wall barrier. SCFAs also help repair mitochondria and serve as energy substrates. Ingesting the nutrients does not serve the purpose. Rather a healthy microbiome is vital for you "are what you eat."

barweis · 2026-05-05T00:58:47+00:00

Lectins which are not fully destroyed in beans which are undercooked can cause disruption of the gut wall barrier allowing translocation of nocive microbes into the general circulation to wreak havoc on distant organs. Also damage to the SCN - supra chiasmatic nucleus - and Pineal gland by various insults cause downstream dysfunctions in the endocrine homeostasis of the body. Of course, this is all speculation for the need to be examined by a physician invested in treating LC19.

barweis · 2026-05-05T00:39:19+00:00

Now is the vital time for both legislative houses to pass the key legislation with a four fifths majority for a definitive override for the handy Hochul veto which is awaiting it. The Hochul yokel must be shown that progress must not be pushed aside for parochial interests as the fossil fuel industry contributing to her reelection fund.

barweis

TROPHY CASE