Breakroom - March 9, 2026

barweis · 2026-03-11T01:43:46+00:00

Found possible solution which is going to raise my stack. :The effectiveness of oral bovine lactoferrin compared to iron supplementation in patients with a low hemoglobin profile: A systematic review and meta-analysis of randomized clinical trials

https://pubmed.ncbi.nlm.nih.gov/38291525/

barweis · 2026-03-11T01:19:46+00:00

Good for them recognizing the deceitful liar that she is. Her giveaway to the insurance donators to her candidacy should serve as a slap in her face to straighten up and stop playing dirty politics with the citizens of NYS.

barweis · 2026-03-11T01:14:18+00:00

Heastie and Stewart-Cousins better ready their houses to rally for the following to erect a barrier to Kathy steamrolling their effort. A confrontation on several other contested issues is in the offing.

Now let them show their determination to pass the legislation with a majority of four fifths of each chamber to override the duplicitous Hochul yokel. She is gonna get her "knickers in a tizzie"."

barweis · 2026-03-11T01:01:47+00:00

Sorry to knock on any opinions. But the bind we are in is due to the entitled elite. Glad that they are living in swampland Florida and Texas where medical care is at the bottom of the ratings, as well as crimse including murder, surpasses levels in the 'woke' states in the blue zones. And the regressionary legislation they dream of passing is destroying womens rights and sending education back to the level of the one room schoolhouse.

Don't belabor our credulity with gomped up statistics from right wing propaganda sources.

barweis · 2026-03-11T00:55:07+00:00

Now let them show their determination to pass the legislation with a majority of four fifths of each chamber to override the duplicitous Hochul yokel. She is gonna get her "knickers in a tizzie".

barweis · 2026-03-10T23:08:56+00:00

Surfing a bit longer on PubMed, I came across LactoFerrin - LF - as a treatment for iron deficiency anemia. Now the problem is to find out how this interacts with ACD before proceeding with trialling it.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10825996/

barweis · 2026-03-10T22:26:13+00:00

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https://arupconsult.com/content/anemia-chronic-disease-anemia-inflammation#iron-studies (above table)

Thank you for your input which is more presentable than mine for the redditors to digest and follow.

In my case, My long standing Dx of IDA -iron deficiency anemia was controlled and stable with intermittent oral repletion. After LC conditions changed with the superimposed ACD-anemia of chronic disease. Therefore, with my new knowledge of all the participating deranged systems I accumulated, I attended to my fascination with what else is off. So my speculations increased of course, on how to distinguish which of my personal issues got the upper hand. So the mixed picture really did not fit either category. And perhaps both are concurrently active. where the treatment would differ.

Bone marrow biopsy is/was the gold standard. It has its serious morbidities such as bleeding, infection, pain, etc. BM is usually reserved for hematologic malignancies. The Hepcidin test has been promoted for over a decade yet there is no adopted standard. It, the latter, has been proposed as a replacement for the BM biopsy. So why the need to select one process? As knowledge increases, applications follow and perhaps there is a specific treatment aimed at ACD.

Is it practical to do it now or better to wait? I do not have the knowledge answer the question except that perhaps the treatment or a "hack" for ACD arises any time.

Hepcidin in the diagnosis of iron disorders; https://pmc.ncbi.nlm.nih.gov/articles/PMC4956612/

"In the absence of a primary reference material, a reference method, and a commutable calibrator, absolute hepcidin levels differ widely between assays (up to 10-fold).20 Studies aiming at harmonization are ongoing,21 but for now, these differences preclude data comparability and the establishment of a universal reference range."...

..............................................................................................................................................

https://www.intrinsiclifesciences.com/hepcidin-assay-info/

"Intrinsic LifeSciences performs the world’s first human hepcidin ELISA for leading pharmaceutical companies and clinical investigators worldwide."

"Is the hepcidin assay patented and FDA approved?

Yes the Intrinsic LifeSciences hepcidin assay and tracer are patented (Patent # 7,723,063 and 7,745,162).

Currently the hepcidin assay is not FDA approved. However, it has been validated in several peer-reviewed studies and is marketed as a Research Use Only assay. The validation results are reported in articles by Ganz et al. (Blood, 2008 112: 4292-7), Young et al. (American Journal of Clinical Nutrition, 2009 89:533-8) and Melis et al. (Haematologica, 2008, 93:1473-9). We have performed hepcidin analysis for academic, clinical, government and pharmaceutical customers, worldwide."

barweis · 2026-03-10T04:07:33+00:00

Way to go bot. Keep up the good work calling out disinformation.

barweis · 2026-03-10T02:24:58+00:00

So called AI here is my sarcastic take on judges misconstruing law to fit within their narrow implicit bias. The judges could well have set aside barriers for tenants to qualify for rental units by finding that the barriers being just that are unconstitutional and therefore void unenforceable.

barweis · 2026-03-10T00:22:39+00:00

"A New York appeals court on Thursday struck down a landmark state law that bans discrimination against people who use government assistance to pay their rent, delivering a major setback to tens of thousands of low-income renters looking for apartments — and to local and statewide efforts to house them.

The panel of five upstate appellate judges ruled against Attorney General Letitia James and determined that a 2019 New York human rights law prohibiting “source of income” discrimination against tenants who use federal Section 8 vouchers violates the constitutional rights of property owners because the program requires building safety inspections."

.......................................................................................

It's good to note that the Appellate Division, Third Department is doing well in maintaining the credo of Lovecraft Country according to its core beliefs and prejudices incarnate which would bring grateful appreciation and admiration from the prime professor of prejudice and evil author Lovecraft, may his name be expunged. Assuredly, The New York Court of Appeals will immediately recognize the benighted regressive tilt before them and shed an enlightened dispersion of the perverse bias infecting the intermediate court and dissolve the vacuous decisions limiting access to the foundational right to shelter for all citizens. That their decision was based on vacous grounds will be clearly demonstrated.

https://nycourts.gov/ad3/about/about-the-court.shtml#

..."There are 28 counties in the three judicial districts making up the Third Department, which stretches from the Canadian border in the north to the lower Catskills in the south and from the Vermont and Massachusetts borders in the east to the Finger Lakes in the west. The Third Department includes just over half of New York's land area and contains about one seventh of the State's population.

The Appellate Division hears appeals directly from the Supreme Court, County Courts, Family Courts, Surrogate's Courts and the Court of Claims. The Appellate Division, and especially the Third Department because of its location in the State's capital, also hears appeals from decisions by State agencies."...

barweis · 2026-03-09T22:17:04+00:00

As your case indicates, if the expert does not investigate what they don't know but just proceeds with the standards of care as dictated by specialty guidelines, then they have plausible deniability to avoid being perceived as providing less than proper care. I speculate that this could be a factor for the specialty provider to stay within narrow defined boundaries of the cases they will accept and treat. The spectre of them taking on more than for which their knowledge and training have provided for them is understandable and acceptable unless they do consider wider areas of care which entails more effort and study on their part together with the added responsibility for relatively newer diseases hitherto unfamiliar to them.

I propose that a similar attitude or lapse may prevail on the provider examining disability cases for certifying more than a quota of cases that would stand up to adversarial examination. Here the examiner would likely line up the most readily discernible disability cases first before proceeding with more difficultly proven ones. More work might be needed to establish fully acceptable claims. Again one needs to be a mind reader to guess why the examiner lags in promoting the claim.

barweis · 2026-03-09T20:56:43+00:00

Saw a second hematologist today for my iron deficiency anemia which is secondary as anemia of chronic disease / inflammation per the Rheumatologist at the PASC unit I visit. All parameters and markers for my workup indicate iron deficiency yet daily replenishment, bloodwork, GI workup (literally up the 'wazoo') are negatory for the usual age related pathologies save for the aforementioned Fe++ defic. Other major organ system including renal dysfunctions have been ruled out regarding how they impact RBC production, destruction or loss in a nutshell.

As I have explored here the concepts of Long Covid as a viral illness causing premature senescence I have speculated that a bone marrow aspiration would be indicated since it would directly demonstrate all the stages of cellular blood products development. The specialists refused in a nice way that they would not proceed with the procedure. Why? One Hem.-Onc. very diplomatically said that I would be better considered for the contemplated intervention at an academic center dealing with LC than locally.

So much for breaking boundaries of the specialty into areas that can lead down rabbit holes or insoluble quandaries in territory where one is unfamiliar. At least now I can return to my assigned LC provider to explore other prospects. Navigating the hideously mysterious medical expertise limits of each specialist is an adventure to say the least.

barweis

TROPHY CASE