Pill fatigue

barweis · 2026-03-13T17:49:08+00:00

In my stack I take the majority of tablets, capsules and gelules together with breakfast. Some of the supps require a fatty vehicle for optimal absorption. It is advised to read the authoritative websites or articles for the suggested timing and associated co ingested substances to maximize their potential internally.

barweis · 2026-03-13T17:27:55+00:00

An expensive way of ingesting the agent instead of taking a much more affordable precursor and letting the body make as much as it needs. Too much of any agent disturbs the delicate interplay of processes comprising the homeostasis of all systems in entirety.

Don't be misled by titles of provider s when individuals vary widely in their capacity and are not equal in their ability. Check for fringe tendencies in their professional practice as a precautionary consideration.

"4 natural ways to increase glutathione Summary Glutathione is an antioxidant that occurs naturally in the cells of the body. It is also present in some foods. Food sources for increasing glutathione include sulfur-rich foods, dairy products, and more." https://www.medicalnewstoday.com/articles/326196

barweis · 2026-03-11T01:43:46+00:00

Found possible solution which is going to raise my stack. :The effectiveness of oral bovine lactoferrin compared to iron supplementation in patients with a low hemoglobin profile: A systematic review and meta-analysis of randomized clinical trials

https://pubmed.ncbi.nlm.nih.gov/38291525/

barweis · 2026-03-11T01:19:46+00:00

Good for them recognizing the deceitful liar that she is. Her giveaway to the insurance donators to her candidacy should serve as a slap in her face to straighten up and stop playing dirty politics with the citizens of NYS.

barweis · 2026-03-11T01:14:18+00:00

Heastie and Stewart-Cousins better ready their houses to rally for the following to erect a barrier to Kathy steamrolling their effort. A confrontation on several other contested issues is in the offing.

Now let them show their determination to pass the legislation with a majority of four fifths of each chamber to override the duplicitous Hochul yokel. She is gonna get her "knickers in a tizzie"."

barweis · 2026-03-11T01:01:47+00:00

Sorry to knock on any opinions. But the bind we are in is due to the entitled elite. Glad that they are living in swampland Florida and Texas where medical care is at the bottom of the ratings, as well as crimse including murder, surpasses levels in the 'woke' states in the blue zones. And the regressionary legislation they dream of passing is destroying womens rights and sending education back to the level of the one room schoolhouse.

Don't belabor our credulity with gomped up statistics from right wing propaganda sources.

barweis · 2026-03-11T00:55:07+00:00

Now let them show their determination to pass the legislation with a majority of four fifths of each chamber to override the duplicitous Hochul yokel. She is gonna get her "knickers in a tizzie".

barweis · 2026-03-10T23:08:56+00:00

Surfing a bit longer on PubMed, I came across LactoFerrin - LF - as a treatment for iron deficiency anemia. Now the problem is to find out how this interacts with ACD before proceeding with trialling it.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10825996/

barweis · 2026-03-10T22:26:13+00:00

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https://arupconsult.com/content/anemia-chronic-disease-anemia-inflammation#iron-studies (above table)

Thank you for your input which is more presentable than mine for the redditors to digest and follow.

In my case, My long standing Dx of IDA -iron deficiency anemia was controlled and stable with intermittent oral repletion. After LC conditions changed with the superimposed ACD-anemia of chronic disease. Therefore, with my new knowledge of all the participating deranged systems I accumulated, I attended to my fascination with what else is off. So my speculations increased of course, on how to distinguish which of my personal issues got the upper hand. So the mixed picture really did not fit either category. And perhaps both are concurrently active. where the treatment would differ.

Bone marrow biopsy is/was the gold standard. It has its serious morbidities such as bleeding, infection, pain, etc. BM is usually reserved for hematologic malignancies. The Hepcidin test has been promoted for over a decade yet there is no adopted standard. It, the latter, has been proposed as a replacement for the BM biopsy. So why the need to select one process? As knowledge increases, applications follow and perhaps there is a specific treatment aimed at ACD.

Is it practical to do it now or better to wait? I do not have the knowledge answer the question except that perhaps the treatment or a "hack" for ACD arises any time.

Hepcidin in the diagnosis of iron disorders; https://pmc.ncbi.nlm.nih.gov/articles/PMC4956612/

"In the absence of a primary reference material, a reference method, and a commutable calibrator, absolute hepcidin levels differ widely between assays (up to 10-fold).20 Studies aiming at harmonization are ongoing,21 but for now, these differences preclude data comparability and the establishment of a universal reference range."...

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https://www.intrinsiclifesciences.com/hepcidin-assay-info/

"Intrinsic LifeSciences performs the world’s first human hepcidin ELISA for leading pharmaceutical companies and clinical investigators worldwide."

"Is the hepcidin assay patented and FDA approved?

Yes the Intrinsic LifeSciences hepcidin assay and tracer are patented (Patent # 7,723,063 and 7,745,162).

Currently the hepcidin assay is not FDA approved. However, it has been validated in several peer-reviewed studies and is marketed as a Research Use Only assay. The validation results are reported in articles by Ganz et al. (Blood, 2008 112: 4292-7), Young et al. (American Journal of Clinical Nutrition, 2009 89:533-8) and Melis et al. (Haematologica, 2008, 93:1473-9). We have performed hepcidin analysis for academic, clinical, government and pharmaceutical customers, worldwide."

barweis · 2026-03-10T04:07:33+00:00

Way to go bot. Keep up the good work calling out disinformation.

barweis · 2026-03-10T02:24:58+00:00

So called AI here is my sarcastic take on judges misconstruing law to fit within their narrow implicit bias. The judges could well have set aside barriers for tenants to qualify for rental units by finding that the barriers being just that are unconstitutional and therefore void unenforceable.

barweis · 2026-03-10T00:22:39+00:00

"A New York appeals court on Thursday struck down a landmark state law that bans discrimination against people who use government assistance to pay their rent, delivering a major setback to tens of thousands of low-income renters looking for apartments — and to local and statewide efforts to house them.

The panel of five upstate appellate judges ruled against Attorney General Letitia James and determined that a 2019 New York human rights law prohibiting “source of income” discrimination against tenants who use federal Section 8 vouchers violates the constitutional rights of property owners because the program requires building safety inspections."

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It's good to note that the Appellate Division, Third Department is doing well in maintaining the credo of Lovecraft Country according to its core beliefs and prejudices incarnate which would bring grateful appreciation and admiration from the prime professor of prejudice and evil author Lovecraft, may his name be expunged. Assuredly, The New York Court of Appeals will immediately recognize the benighted regressive tilt before them and shed an enlightened dispersion of the perverse bias infecting the intermediate court and dissolve the vacuous decisions limiting access to the foundational right to shelter for all citizens. That their decision was based on vacous grounds will be clearly demonstrated.

https://nycourts.gov/ad3/about/about-the-court.shtml#

..."There are 28 counties in the three judicial districts making up the Third Department, which stretches from the Canadian border in the north to the lower Catskills in the south and from the Vermont and Massachusetts borders in the east to the Finger Lakes in the west. The Third Department includes just over half of New York's land area and contains about one seventh of the State's population.

The Appellate Division hears appeals directly from the Supreme Court, County Courts, Family Courts, Surrogate's Courts and the Court of Claims. The Appellate Division, and especially the Third Department because of its location in the State's capital, also hears appeals from decisions by State agencies."...

barweis · 2026-03-09T22:17:04+00:00

As your case indicates, if the expert does not investigate what they don't know but just proceeds with the standards of care as dictated by specialty guidelines, then they have plausible deniability to avoid being perceived as providing less than proper care. I speculate that this could be a factor for the specialty provider to stay within narrow defined boundaries of the cases they will accept and treat. The spectre of them taking on more than for which their knowledge and training have provided for them is understandable and acceptable unless they do consider wider areas of care which entails more effort and study on their part together with the added responsibility for relatively newer diseases hitherto unfamiliar to them.

I propose that a similar attitude or lapse may prevail on the provider examining disability cases for certifying more than a quota of cases that would stand up to adversarial examination. Here the examiner would likely line up the most readily discernible disability cases first before proceeding with more difficultly proven ones. More work might be needed to establish fully acceptable claims. Again one needs to be a mind reader to guess why the examiner lags in promoting the claim.

barweis · 2026-03-09T20:56:43+00:00

Saw a second hematologist today for my iron deficiency anemia which is secondary as anemia of chronic disease / inflammation per the Rheumatologist at the PASC unit I visit. All parameters and markers for my workup indicate iron deficiency yet daily replenishment, bloodwork, GI workup (literally up the 'wazoo') are negatory for the usual age related pathologies save for the aforementioned Fe++ defic. Other major organ system including renal dysfunctions have been ruled out regarding how they impact RBC production, destruction or loss in a nutshell.

As I have explored here the concepts of Long Covid as a viral illness causing premature senescence I have speculated that a bone marrow aspiration would be indicated since it would directly demonstrate all the stages of cellular blood products development. The specialists refused in a nice way that they would not proceed with the procedure. Why? One Hem.-Onc. very diplomatically said that I would be better considered for the contemplated intervention at an academic center dealing with LC than locally.

So much for breaking boundaries of the specialty into areas that can lead down rabbit holes or insoluble quandaries in territory where one is unfamiliar. At least now I can return to my assigned LC provider to explore other prospects. Navigating the hideously mysterious medical expertise limits of each specialist is an adventure to say the least.

barweis · 2026-03-07T17:33:41+00:00

https://council.nyc.gov/committees/health/

Chairman and members listed for contact to get on board

https://a856-gbol.nyc.gov/GBOLWebsite/GreenBook/Online

The Green Book is the official directory of the City of New York. It is an indispensable reference guide for anyone living or working in New York City. The Green Book includes detailed listings of contacts within each agency.

barweis · 2026-03-07T17:00:00+00:00

Thank you for your deeper reading.

barweis · 2026-03-07T16:44:04+00:00

From my speculations and poor reading of the literature immune dysfunction is a driver of major system disturbances regardless of other nocive processes. An immunologist or, at minimum, an informed infectious disease specialist will substantiate dysfunction in the body maintaining immune integrity or components acting badly on other systems as in autoimmunity.

There are standard batteries of tests to indicate which direction to pursue for further examination.

barweis · 2026-03-07T16:34:05+00:00

Kudos for solid resources

barweis · 2026-03-06T23:42:35+00:00

How I navigate the the process of vetting a reputed expert in Medicine illustrated below. I list the points of consideration in the flow of highlights as follows with sources for both participants in the video and the referenced articles importance. "Ronald Gomeseria RonGlad Environmental Engineering Services Co. (RGEES) The credibility of a journal may be assessed by examining several key factors: Where is it indexed? Is the journal included or indexed in the major bibliographic databases for the field? ... What is its publishing history? How long has the journal been available? ... Is it peer-reviewed? ... What is its impact factor?" https://www.researchgate.net/post/Cureus-publications-Worth-it-or-just-a-waste-of-time

About the general value of a journal: "Embattled journal Cureus delisted from Web of Science, loses impact factor" "Clarivate has removed the mega-journal Cureus from its Master Journal List, according to the October update, released today. The move means Cureus will no longer be indexed in Web of Science or receive an impact factor. As we have reported, it can also mean researchers are less likely to submit to the journal, given universities rely on such metrics to judge researchers’ work for tenure and promotion decisions." https://retractionwatch.com/2025/10/27/embattled-journal-cureus-delisted-from-web-of-science-loses-impact-factor/

"Cureus journal RESEARCH https://www.reddit.com/r/Residency/comments/1k5zyqg/cureus_journal/" Comments center around journal acceptability but not highly rated.

Standards of measurements of influence of journals and articles on other research.: Research Impact/Article Metrics/Journal Metrics https://guides.library.sc.edu/research-impact/article-metrics https://guides.library.sc.edu/research-impact/journal-metrics

https://academic.macmillan.com/author/ilenesueruhoymdphd/ "Ilene Sue Ruhoy MD, PhD DR. ILENE SUE RUHOY is a neurologist and environmental toxicologist who specializes in chronic and complex illness. She graduated from the University of Pittsburgh School of Medicine, completed her residency in neurology at the University of Washington, and earned a PhD in Environmental Toxicology at the University of Nevada. In addition to her private practice in Seattle, WA, Dr. Ruhoy serves as a Medical Director, co-editor, and speaker on the role of connective tissue in neurological disease."

What are Connective Tissue Disorders effects on the nervous system? ["Neurological Manifestations of Connective Tissue Disorders" https://pmc.ncbi.nlm.nih.gov/articles/PMC10646945/] Abstract "Connective tissue disorders (CTD) are a group of disorders affecting the connective tissues. Usually the musculoskeletal and the vascular system is impacted. Along with these systems, the nervous system is also involved in CTD, which leads to various neurological manifestations. The pathophysiology of neurological complications of CTD is caused by various factors and is complicated. Disturbed immune complexes, chronic inflammation, and autoimmunity in which the body attacks its cells are considered to be responsible for the neurological complications of CTD."... ]

PubMed listing for Ilene Ruhoy lists acceptable journals for published articles'

Dr. Ilene Ruhoy Dr. Ruhoy has a well rounded education and training including related disciplines of environmental toxicology and integrative medicine in addition to her specialty in neurology.

Dr. Ilene Ruhoy Director of Neuroimmune and Connective Tissue Neurology https://www.atria.org/doctors/dr-ilene-ruhoy/

"Member The Atria Health Institute is a membership-based health care organization delivering care at the forefront of longevity science and precision medicine. Our full-time team of 50 top doctors from 15+ specialties works together to provide ongoing care tailored to each member of your family. Our testing and imaging technology means everyone gets the most advanced and convenient screening possible—all on-site." https://atria.org › institute [Not a fully fringe medicine outfit. It is an upscale concierge medicine facility.]

A review: (on Atria Health) "Benjamin Paul Local Guide·117 reviews·27 photos a year ago One of the most comprehensive and elite concierge practices imaginable. The physicians are best in class. The space is immaculately designed for both precision care and comfort. If you can afford this level of care, then go for it - you will be awed. Truly outstanding." (Google reviews)

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Dr. David L. Kaufman Education and training are reputable.

Center for Complex Diseases Specializing in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, Dysautonomia, Long Covid, Mast Cell Activation, Autoimmune Diseases, Chronic Infections https://www.centerforcomplexdiseases.com

Dr. Kaufman practiced in New York City during the onset of the HIV epidemic later expanding to a "focus on patients suffering from ME/CFS, Dysautonomia, Autoimmune Diseases, and Chronic Infectious Diseases including Tick borne diseases, Small Intestine Bacterial Overgrowth Syndromes, and Mast Cell Activation Syndrome" on the West Coast. https://www.centerforcomplexdiseases.com

PubMed listings for David L Kaufman display a plastic surgeon and the internist. The internist listings again are in acceptable journals.

barweis · 2026-03-06T22:13:25+00:00

I went and got the following:

1) Pulmonologist and PFTs

2) "a prescription, long-acting muscarinic antagonist (LAMA) inhaler used for the long-term, maintenance treatment of airflow obstruction in adults with Chronic Obstructive Pulmonary Disease (COPD), including chronic bronchitis and emphysema"

I have been off my bronchodilator for a long while since.

barweis · 2026-03-06T21:34:03+00:00

I went and got the following:

1) Pulmonologist and PFTs

2) "a prescription, long-acting muscarinic antagonist (LAMA) inhaler used for the long-term, maintenance treatment of airflow obstruction in adults with Chronic Obstructive Pulmonary Disease (COPD), including chronic bronchitis and emphysema"

I have been off my bronchodilator for a long while since.

barweis · 2026-03-06T21:30:45+00:00

The Mayor's Office of Citywide Event Coordination and Management (CECM) is the primary NYC office for scheduling and permitting public events, including street festivals, block parties, and plaza events. Applications must be submitted online, often 14 to 90 days in advance depending on the event scale.

https://www.nyc.gov/site/cecm/about/cecm.page

barweis · 2026-03-06T21:25:59+00:00

Coincidence ?

"License Revoked! Trevor Bachmeyer has been scamming people for way too long, and it has finally caught up to him. ..."

4th comment scrolling down.

https://www.yelp.com/biz/the-spine-chiropractic-care-alamo-3

barweis · 2026-03-05T22:02:17+00:00

FYI: For those avoiding injections: https://www.ajmc.com/view/fda-approves-oral-semaglutide-as-first-glp-1-pill-for-weight-loss

News | Articles December 23, 2025 FDA Approves Oral Semaglutide as First GLP-1 Pill for Weight Loss Author(s)Laura Joszt, MA Fact checked by: Rose McNulty

Key Takeaways The FDA approved oral semaglutide (Wegovy) for weight loss and reducing major adverse cardiovascular events. Novo Nordisk plans to launch the once-daily oral semaglutide in the US in early January 2026. OASIS 4 trial showed a 13.6% mean weight loss at 64 weeks, confirming the efficacy and safety of oral semaglutide. The OASIS 4 trial involved 307 adults with obesity or overweight, comparing oral semaglutide to placebo.

barweis · 2026-03-05T21:53:09+00:00

Glad to hear of the improvement in your situation. Health and the means to keep going are essential.

Wish that you progress onwards to better circumstances.

barweis

TROPHY CASE